Squalene epoxidase / SQLE antibody

Principal name

Squalene epoxidase / SQLE antibody

Alternative names for Squalene epoxidase / SQLE antibody

Squalene monooxygenase, ERG1

SwissProt ID

P32476 (Yeast), P52019 (Mouse), P52020 (Rat), Q14534 (Human), Q9C1W3 (Schpo)

Gene ID

6713 (SQLE)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), Hst (Hamster)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of Squalene epoxidase / SQLE antibody

SQLE, also med as ERG1, SE and SM, belongs to the squalene monooxygese family. It catalyzes the first oxygetion step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslatiolly regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.

General readings

Bailey, S.D., et al. Diabetes Care 33(10): 2250-2253 (2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5): 628-642 (2009)
Lu, Y., et al. J. Lipid Res. 49(12): 2582-2589 (2008)
Helms, M.W., et al. Br. J. Cancer 99(5): 774-780 (2008)
Liu, Y., et al. Lung Cancer 56(3): 307-317 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Squalene epoxidase / SQLE antibody

Human Brain; . Rabbit Anti-SQLE Antibody. . Catalog Number:. ARP42101 . Paraffin Embedded Tissue: Human neural cell . Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X Rabbit Purified Bov, Can, Hu, Ms, Por, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

Squalene epoxidase / SQLE (N-term) antibody

Immunohistochemistry analysis in human testis tissue (Formalin-fixed, Paraffin-embedded) using Squalene epoxidase / SQLE antibody Cat.-No. AP54036PU-N (N-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SQLE antibody for IHC; Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Squalene epoxidase / SQLE antibody

Western Blot analysis of SQLE expression in transfected 293T cell line (H00006713-T01) by SQLE MaxPab polyclonal antibody.

Lane 1: SQLE transfected lysate(63.14 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Squalene epoxidase / SQLE antibody

Squalene epoxidase / SQLE Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Squalene epoxidase / SQLE antibody

Squalene epoxidase / SQLE Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Ze P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Squalene epoxidase / SQLE

Squalene epoxidase / SQLE Human
2 µg / €300.00
  Abnova Taiwan Corp.

Squalene epoxidase / SQLE

Squalene epoxidase / SQLE Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Squalene epoxidase / SQLE

Squalene epoxidase / SQLE Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Squalene epoxidase / SQLE

Squalene epoxidase / SQLE Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SQLE 293T Cell Transient Overexpression Lysate(Denatured)

SQLE 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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