SS-B / La antibody

Principal name

SS-B / La antibody

Alternative names for SS-B / La antibody

SSB, Sjoegren syndrome type B antigen, Lupus La protein, La ribonucleoprotein, La autoantigen, LARP3

SwissProt ID

P05455 (Human), P10881 (Bovin), P32067 (Mouse), P38656 (Rat), P40796 (Drome), Q04504 (Rabit)

Gene ID

6741 (SSB)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), African clawed frog, Mky (Monkey)

Available hosts

Human, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F), Luminex (LMNX)

Background of SS-B / La antibody

SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]. Sequence Note: removed 1 base from the 3\' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1673 BC020818.1 1-1673

General readings

Cordes,S., (2008) Biochem. Biophys. Res. Commun. 368 (4), 1014-1019

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SS-B / La antibody

Anti-SSB mouse monoclonal antibody (TA500406) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SSB(RC205013). Mouse IgG2a OTI1E11 Purified Can, Hu, Mky, Ms, Rt F, ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SSB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500407) Mouse IgG3 OTI9D6 Purified Can, Hu, Mky F, ICC/IF, IP, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SSB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500410) Mouse IgG2a OTI3H9 Purified Can, Hu F, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SSB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500426) Mouse IgG1 OTI2C8 Purified Can, Hu, Mky ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SSB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500427) Mouse IgG1 OTI6G7 Purified Can, Hu, Mky ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-SSB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500436) Mouse IgG1 OTI3F11 Purified Can, Hu, Mky ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SS-B / La antibody

SSB polyclonal antibody (A01), Lot # FAK0060323QCS1. Western Blot analysis of SSB expression in NIH/3T3. Mouse Serum Hu, Ms, Rt E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

SS-B / La antibody

Human Heart; . Rabbit Anti-SSB Antibody. . Catalog Number:. ARP40462 . Paraffin Embedded Tissue: Human cardiac cell . Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

SS-B / La antibody

Immunohistochemistry-Paraffin: SSB Antibody (2C8) [NBP1-48002] - Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-SSBmouse monoclonal antibody. (Dilution 1:50) Mouse 2C8 Aff - Purified Can, Hu, Mky ICC/IF, IP, P, WB
0.1 ml / €530.00
  Novus Biologicals Inc.

SS-B / La antibody

Predicted cell location: Nucleus. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using SSB antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SS-B / La antibody

Predicted cell location: Nucleus. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using SSB antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SS-B / La antibody

SSB Luminex with 1E11 Capture (TA600522) and 9D6 Detection (TA700522) Antibodies. Substrate used: Recombinant Human SSB (TP305013) Mouse IgG1 OTI1E11 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

SS-B / La antibody

SSB Luminex with 6G7 Capture (TA600523) and 1E11 Detection (TA700523) Antibodies. Substrate used: Recombinant Human SSB (TP305013) Mouse IgG1 OTI6G7 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

SS-B / La antibody

SSB Luminex with 9D6 Capture (TA600524) and 1E11 Detection (TA700523) Antibodies. Substrate used: Recombinant Human SSB (TP305013) Mouse IgG1 OTI9D6 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

SS-B / La antibody

SSB Luminex with 1E11 Capture (TA600522) and 9D6 Detection (TA700522) Antibodies. Substrate used: Recombinant Human SSB (TP305013) Mouse IgG1 OTI9D6 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

SS-B / La antibody

SSB Luminex with 6G7 Capture (TA600523) and 1E11 Detection (TA700523) Antibodies. Substrate used: Recombinant Human SSB (TP305013) Mouse IgG1 OTI1E11 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

SS-B / La (C-term) antibody

Western blot analysis of anti-SSB Antibody (C-term) (Cat.#AP12452PU-N) in Hela cell line lysates (35ug/lane). SSB(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SS-B / La antibody

Western blot analysis of SSB antibody (Cat.-No.: AP20317PU-N) in extracts from 293 cells. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SS-B / La antibody

SS-B / La Human Ig Fraction Hu E, ID
2 ml / €280.00
  Acris Antibodies GmbH

SS-B / La antibody

SS-B / La Mouse Hu ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

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