SSTR3 antibody

Principal name

SSTR3 antibody

Alternative names for SSTR3 antibody

Somatostatin receptor type 3, SS-3-R, SS3-R, SS3R, SSR-28

SwissProt ID

P30935 (Mouse), P30936 (Rat), P32745 (Human), Q9P7S3 (Schpo)

Gene ID

6753 (SSTR3), 171044 (Sstr3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of SSTR3 antibody

Somatostatin (SST) is a small cyclic peptide that was first identified as a powerful inhibitor of the secretion of various hormones including growth hormone (GH), thyroid-stimulating hormone (TSH) and prolactin from the pituitary, as well as practically every major hormone from the intestil tract. SST consists of two major bioactive forms, SST-14 and the N-terminus extended peptide SST-28 that can be produced by a wide variety of neuroendocrine, inflammatory and immune cells. SST induces in target cells a variety of physiological functions that include nueromodulation, cell secretion, cell proliferation and smooth muscle contractility. SST acts on its multiple cell targets via a family of six receptors that are origited form five genes: SSTR1, SSTR2a, SSTR2b, SSTRR3, SSTR4, SSTR5. The SSTRs are members of the G-protein coupled receptor superfamily and they modulate cell response via multiple second messenger systems such as inhibition of adenylate cyclase, modulation of conductance of ion channels and protein dephosphorylation. SSTRs are expressed widely in both the brain and peripheral tissues but with receptor subtype variations between the different cell types. Thus, SSTR3 expression in the brain is primarily concentrated in the cerebellum with lesser expression in peripheral organs such as the spleen, the liver and the pituitary. Strong SSTR expression has been detected in a variety of human tumors including pancreatic, breast, lung and prostate cancers. In fact, SST has been shown to inhibit the growth of various normal and tumor cells. On this basis several long lasting SST alogs have been developed and are being tested for use in several pathologies such as various cancers, acromegaly, immunoproliferative disorders, diabetic retinopathy, epilepsy and pain.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SSTR3 (C-term) antibody

Anti-SSTR3 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

SSTR3 antibody

Western blot analysis of extracts from A549 cells, using SSTR3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR3 antibody

Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SSTR3 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR3 antibody

Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using SSTR3 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR3 antibody

Western blot analysis of rat brain lysate: 1. Anti-Somatostatin Receptor Type 3 antibody  , (1:200). 2. Anti-Somatostatin Receptor Type 3 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SSTR3 antibody

Immunohistochemistry: Somatostatin Receptor 3 Antibody [NB100-74538] - Immunohistochemical staining of SSTR3 in human pancreatic islands using NB100-74538. Rabbit Serum Hu ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

SSTR3 antibody

SSTR3 Rabbit Aff - Purified Hu P
50 µl / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SSTR3

SSTR3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SSTR3 overexpression lysate

SSTR3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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