SSTR4 antibody

Principal name

SSTR4 antibody

Alternative names for SSTR4 antibody

Somatostatin receptor type 4, SS-4-R, SS4-R, SS4R

SwissProt ID

P30937 (Rat), P31391 (Human), P49660 (Mouse), Q9P7Y0 (Schpo)

Gene ID

6754 (SSTR4), 25555 (Sstr4)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of SSTR4 antibody

Somatostatin (SST) is a small cyclic peptide that was first identified as a powerful inhibitor of the secretion of various hormones including growth hormone (GH), thyroid-stimulating hormone (TSH) and prolactin from the pituitary, as well as practically every major hormone from the intestil tract. SST consists of two major bioactive forms, SST-14 and the N-terminus extended peptide SST-28 that can be produced by a wide variety of neuroendocrine, inflammatory and immune cells. In target cells SST induces a variety of physiological functions that include neuromodulation, cell secretion, cell proliferation and smooth muscle contractility. SST acts on its multiple cell targets via a family of six receptors that origite from five genes: SSTR1, SSTR2a, SSTR2b, SSTRR3, SSTR4, SSTR5. The SSTRs are members of the G-protein coupled receptor superfamily and they modulate cell response via multiple second messenger systems such as inhibition of adenylate cyclase, modulation of conductance of ion channels and protein dephosphorylation. SSTRs are expressed widely in both the brain and peripheral tissues but with receptor subtype variations between the different cell types. Thus, SSTR4 is the least SSTR subtype expressed in the brain but is most strongly expressed in the lung, heart and placenta. Strong SSTR expression has been detected in a variety of human tumors including pancreatic, breast, lung and prostate cancers. In fact, SST has been shown to inhibit the growth of various normal and tumor cells. On this basis, several long lasting SST alogs have been developed and are being tested for use in several pathologies such as various cancers, acromegaly, immunoproliferative disorders, diabetic retinopathy, epilepsy and pain.

General readings

Pasquali,D., et al., (2002) J. Clin. Endocrinol. Metab. 87 (11), 5125-5129

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SSTR4 antibody

Western blot analysis of extracts from LOVO cells, using SSTR4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR4 antibody

Predicted cell location: Cytoplasm,cell membrane. Positive control: Human brain tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using SSTR4 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR4 antibody

Predicted cell location: Cytoplasm,cell membrane. Positive control: Human brain tissue . Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using SSTR4 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR4 antibody

Western blot analysis of rat brain lysate: 1. Anti-Somatostatin Receptor Type 4 (extracellular) antibody,   (1:200). 2. Anti-Somatostatin Receptor Type 4 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SSTR4 antibody

SSTR4 Rabbit IgG Purified Ms, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

SSTR4 antibody

SSTR4 Rabbit IgG Purified Ms, Rb WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SSTR4 (N-term, Extracel. Dom.) antibody

Anti-SSTR4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

SSTR4 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SSTR4 (RC217543, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SSTR4.(1:2000) Mouse IgG1 OTI2F11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SSTR4 antibody

Western blot (WB) analysis of SSTR4 Antibody Cat.-No AP01432PU-N in extracts from LOVO cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

SSTR4 antibody

Western blot analysis of extracts from LOVO cells, using SSTR4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

SSTR4 antibody

Western blot analysis of extracts from LOVO cells, using SSTR4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

SSTR4 antibody

Human Jurkat; WB Suggested Anti-SSTR4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; SSTR4 antibody - middle region (ARP33359_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SSTR4 antibody

Human Jurkat; WB Suggested Anti-SSTR4 Antibody. . Titration: 1.25 ug/ml. . Positive Control: Jurkat Whole Cell; SSTR4 antibody - middle region (ARP33359_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

SSTR4 antibody

Western Blot: SSTR4 Antibody [NBP1-01023] - Western blot (WB) analysis of SSTR4 (Q194)  antibody in extracts from LOVO cells Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €420.00
  Novus Biologicals Inc.

SSTR4 antibody

Immunohistochemistry-Paraffin: Somatostatin Receptor 4 Antibody [NLS4148] - Anterior Pituitary Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SSTR4 overexpression lysate

SSTR4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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