SSTR5 antibody

Principal name

SSTR5 antibody

Alternative names for SSTR5 antibody

Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R

SwissProt ID

F1MV99, O08858 (Mouse), P30938 (Rat), P35346 (Human)

Gene ID

6755 (SSTR5), 25354

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), ELISA (detection) (E(detection))

Background of SSTR5 antibody

Somatostatin (SST) is a small cyclic peptide that was first identified as a powerful inhibitor of the secretion of various hormones including growth hormone (GH), thyroid-stimulating hormone (TSH) and prolactin from the pituitary, as well as practically every major hormone from the intestil tract. SST consists of two major bioactive forms, SST-14 and the N-terminus extended peptide SST-28, that can be produced by a wide variety of neuroendocrine, inflammatory and immune cells. In target cells, SST induces a variety of physiological functions that include neuromodulation, cell secretion, cell proliferation and smooth muscle contractility. SST acts on its multiple cell targets via a family of six receptors that origite from five genes: SSTR1, SSTR2a, SSTR2b, SSTRR3, SSTR4, SSTR5. The SSTRs are members of the G-protein coupled receptor superfamily and they modulate cell response via multiple second messenger systems such as inhibition of adenylate cyclase, modulation of conductance of ion channels and protein dephosphorylation. In contrast to SSTR1-4 that bind SST-14 and SST-28 with similar affinity, SSTR5 has a much greater affinity to SST-28 over SST-14. SSTRs are widely expressed in both brain and peripheral tissues but with receptor subtype variations between the different cell types. Strong SSTR expression has been detected in a variety of human tumors including pancreatic, breast, lung and prostate cancers. In fact, SST has been shown to inhibit the growth of various normal and tumor cells. On this basis, several long lasting SST alogs have been developed and are being tested for use in several pathologies such as various cancers, acromegaly, immunoproliferative disorders, diabetic retinopathy, epilepsy and pain. SSTR5 is expressed in a variety of tissues and cells, including pancreas, colonic mucosa, small intestine, heart, and vascular smooth muscle cells. SSTR5 has been shown to mediate growth inhibition and cell proliferation, and to play an important role in cancer growth regulation as one of the most potent inhibitory receptors.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SSTR5 (C-term) antibody

Anti-SSTR5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

SSTR5 (C-term) antibody

Anti-SSTR5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Gorilla, Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

SSTR5 (2nd Extracell. Dom.) antibody

Anti-SSTR5 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Prim P
50 µg / €345.00
  OriGene Technologies, Inc.

SSTR5 antibody

Predicted band size: 39 kDa . Positive control: Mouse thymus tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR5 antibody

Predicted band size: 39 kDa . Positive control: Human liver cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SSTR5 antibody

Western blot analysis of rat brain lysates: 1. Anti-Somatostatin Receptor Type 5 (extracellular) antibody, (1:200). 2. Anti-Somatostatin Receptor Type 5 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

SSTR5 antibody

Western Blot analysis of SSTR5 expression in transfected 293T cell line (H00006755-T02) by SSTR5 MaxPab polyclonal antibody.

Lane 1: SSTR5 transfected lysate(40.04 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

SSTR5 antibody

IHC analysis of human placenta. Using SSTR5 polyclonal antibody ( Cat # PAB0299 ) at 10 µg/ml. Rabbit Hu C, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SSTR5 antibody

Western Blot: Somatostatin Receptor 5 Antibody [NB100-74540] - Western blot of SSTR5 in human pituitary gland using NB100-74540. Rabbit Serum Hu ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

SSTR5 antibody

SSTR5 Rabbit Purified Ms, Rt ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

SSTR5 antibody

Pancreas Rabbit Aff - Purified Hu P

Regular Price: 50 µl / €440.00

Special Price: 50 µl / €266.00

  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SSTR5

SSTR5 Human
2 µg / €450.00
  Abnova Taiwan Corp.

SSTR5

SSTR5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SSTR5

SSTR5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

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