ST13 / HIP antibody

Principal name

ST13 / HIP antibody

Alternative names for ST13 / HIP antibody

Hsc70-interacting protein, FAM10A1, NY-REN-33, SNC6, Suppression of tumorigenicity 13 protein, Putative tumor suppressor ST13, Progesterone receptor-associated p48 protein

SwissProt ID

C4NYP8 (Drome), P50502 (Human), P50503 (Rat), Q5ZLF0 (Chick), Q99L47 (Mouse)

Gene ID

6767 (ST13), 70356 (St13)

Available reactivities

Hu (Human), Ms (Mouse), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ST13 / HIP antibody

ST13(Suppression of Tumorigenicity 13), also known as P48 or HIP, is a protein that in humans is encoded by the ST13 gene. ST13 is an abundant, highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD (HSP70) and HSP90 during an intermediate stage of steroid receptor assembly, but is absent from the mature receptor complex. Zhang et al. (1998) mapped the ST13 gene to chromosome 22q13 by fluorescence in situ hybridization. They noted that colorectal, breast, and ovarian carcinomas frequently show loss of heterozygosity at this site. Using a yeast 2-hybrid assay, Hohfeld et al. (1995) showed that rat Hip bound Hsc70 (HSPA8). One Hip oligomer bound the ATPase domains of at least 2 Hsc70 molecules, and binding was dependent on activation of the Hsc70 ATPase by Hsp40 (DNAJB1). Hip stabilized the ADP-bound form of Hsc70, which had a high affinity for a test protein substrate. Hohfeld et al. (1995) concluded that HIP contributes to interactions of HSC70 with target proteins through its own chaperone activity.

General readings

Nelson GM., et al. (2004). Mol Endocrinol. 18(7):1620-30.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ST13 / HIP antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer (A), colon cancer (B) using ST13 mouse mAb with DAB staining. Mouse IgG1 3B10 Ascites Hu, Mky E, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

ST13 / HIP antibody

  Rabbit Polyclonal Anti-St13 Antibody - N-terminal region  
Host: Rabbit; Target Name: St13; Sample Tissue: Mouse Heart lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

ST13 / HIP antibody

ST13 / HIP Mouse IgG2a AT5C6 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

ST13 / HIP antibody

ST13 / HIP Mouse IgG2a AT5C6 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

ST13 / HIP (60-75) antibody

Figure 1. Staining ST13 (HIP) in Adrenal by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

ST13 / HIP (N-term) antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with ST13 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ST13 - human gene knockout kit via CRISPR

ST13 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ST13 - human gene knockout kit via CRISPR

ST13 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ST13 - human gene knockout kit via CRISPR

ST13 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ST13 - human gene knockout kit via CRISPR

ST13 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ST13 / HIP

  Recombinant protein of human suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13)  
ST13 / HIP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ST13 / HIP (1-369)

ST13 / HIP Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

ST13 / HIP (1-369)

ST13 / HIP Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ST13 (mGFP-tagged) - Human suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13), 200 uL, >10^7 TU/mL

Lenti ORF particles, ST13 (mGFP-tagged) - Human suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ST13 (Myc-DDK tagged) - Human suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ST13 (Myc-DDK tagged) - Human suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) (ST13) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, St13 (GFP-tagged) - Mouse suppression of tumorigenicity 13 (St13), 200 uL, >10^7 TU/mL

Lenti ORF particles, St13 (GFP-tagged) - Mouse suppression of tumorigenicity 13 (St13), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, St13 (Myc-DDK-tagged) - Mouse suppression of tumorigenicity 13 (St13), 200 uL, >10^7 TU/mL

Lenti ORF particles, St13 (Myc-DDK-tagged) - Mouse suppression of tumorigenicity 13 (St13), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

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