STARD3 antibody

Principal name

STARD3 antibody

Alternative names for STARD3 antibody

CAB1, MLN64, StAR-related lipid transfer protein 3, START domain-containing protein 3, Metastatic lymph node protein 64

SwissProt ID

Q14849 (Human), Q61542 (Mouse)

Gene ID

10948 (STARD3)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP)

Background of STARD3 antibody

The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN 64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN 64 are deleted, the resulting N-218 MLN 64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN 64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN 64 is similar to the organization of StAR. However, as MLN 64 never enters the mitochondria, the protease-resistant domain of MLN 64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.

General readings

General / background references:Alpy F et al. The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein. J Biol Chem 276:4261-9 (2001). PubMed PMID: 11053434
Bose HS et al. N-218 MLN64, a protein with StAR-like steroidogenic activity, is folded and cleaved similarly to StAR. Biochemistry 39:11722-31 (2000). PubMed PMID: 10995240

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STARD3 antibody

Immunohistochemistry: STARD3 Antibody - Normal and malignant tissues generally displayed moderate to strong cytoplasmic immunoreactivity. Strong positivity was noted in both hepatocellular and cholangiocarcinomas though normal hepatocytes were moderately stained. Other strongly positive cancers included endometrial, urothelial, renal and gastro-intestinal cancers. Other cancers were generally moderately positive.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit IgG Purified Hu E, P
50 µg / €325.00
  OriGene Technologies, Inc.

STARD3 antibody

STARD3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

STARD3 antibody

Western Blot analysis of STARD3 expression in transfected 293T cell line by STARD3 monoclonal antibody (M01), clone 1D1.

Lane 1: STARD3 transfected lysate(50.5 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 1D1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STARD3 antibody

Immunohistochemistry: STARD3 Antibody [21570002] - Normal and malignant tissues generally displayed moderate to strong cytoplasmic immunoreactivity. Strong positivity was noted in both hepatocellular and cholangiocarcinomas though normal hepatocytes were moderately stained. Other strongly positive cancers included endometrial, urothelial, renal and gastro-intestinal cancers. Other cancers were generally moderately positive.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit Hu E, P
50 µg / €400.00
  Novus Biologicals Inc.

STARD3 antibody

Western Blot: MLN 64 Antibody [NB300-599] - Figure 1 shows a Western blot of MLN64 on rat adrenal gland extract using NB300-599. Rabbit Aff - Purified Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

STARD3

STARD3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

STARD3

STARD3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

STARD3

STARD3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

STARD3

STARD3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

STARD3 overexpression lysate

STARD3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

STARD3 overexpression lysate

STARD3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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