STAT5B antibody

Principal name

STAT5B antibody

Alternative names for STAT5B antibody

STAT-5B, Signal transducer and activator of transcription 5B

SwissProt ID

P42232 (Mouse), P51692 (Human), P52632 (Rat), Q9TUM3 (Bovin), Q9TUZ0 (Pig)

Gene ID

6777 (STAT5B), 20851 (Stat5b), 25126

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Immunoprecipitation (IP)

Background of STAT5B antibody

STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Mohankumar,K.M., (2008) Endocrinology 149 (5), 2219-2229

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STAT5B antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 5D6 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

STAT5B antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 2D1 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

STAT5B antibody

Immunoperoxidase of monoclonal antibody to STAT5B on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 2 ug/ml] Mouse IgG1 5D6 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STAT5B antibody

Immunoperoxidase of monoclonal antibody to STAT5B on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 1.5 ug/ml] Mouse IgG1 2D1 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STAT5B antibody

Human prostate; Anti-STAT5B antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.; STAT5B antibody - N-terminal region (ARP39000_P050) in Human prostate cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

STAT5B antibody

  Rabbit polyclonal STAT5B (Ser731) antibody(Phospho-specific)  
Western blot analysis of extracts from RAW264.7 cells, treated with EGF (200ng/ml, 30mins), using STAT5B (phospho-Ser731) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Rabbit polyclonal STAT5B (Ab-731) antibody  
Western blot analysis of extracts from RAW264.7 cells, treated with EGF (200ng/ml 30min), using STAT5B (Ab-731) antibody (#TA314575, Line 1 and 2).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Anti-STAT5B Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human tonsil and lymphoma tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue  using STAT5B antibody at dilution 1/10, on the right is immunohistochemistry of paraffin-embedded Human lymphoma cancer tissue using STAT5B antibody at dilution 1/10. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Anti-STAT5B rabbit polyclonal antibody  
Predicted band size: 45kDa. Positive control: SKOV3 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate:50 ug Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B (C-term) antibody

  Rabbit polyclonal STAT5b Antibody (C-term)  
STAT5b Antibody (Cat. #TA324586) western blot analysis in HL-60,MCF-7,mouse NIH/3T3 cell line, rat liver and spleen lysates (35ug/lane).This demonstrates the STAT5b antibody detected the STAT5b protein (arrow). Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Rabbit Polyclonal STAT5B Antibody  
Western blot analysis of STAT5B expression in RAW264.7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Rabbit Polyclonal STAT5B (Ser731) Antibody (Phospho-specific)  
Western blot analysis of STAT5B phosphorylation expression in RAW264.7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  STAT5B Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using STAT5B antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

  Rabbit Polyclonal anti-STAT5 Phospho (Tyr694) Antibody  
U937 whole cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with polyclonal anti-STAT5 pY694 (Poly6511) antibody. Proteins were visualized using anti-rabbit IgG secondary antibody conjugated to HRP and chemiluminescence detection. Lane 1 - lysate from untreated U937 cells treated with 10 ng/ml human GM-CSF for 30 minutes. The same blot was stripped and re-probed with ß-actin antibody (Poly6221) to ensure equal amounts of lysates were loaded in both lanes. Rabbit Poly6511 Purified Hu WB
0.1 mg / €248.00
  OriGene Technologies, Inc.

STAT5B antibody

  Rabbit Polyclonal STAT5B Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT5B (RC209429, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT5B. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STAT5B antibody

Western blot analysis using STAT5B mouse mAb against Hela (1), K562 (2), NIH/3T3 (3), C6 (4), HEK293 (5), Jurkat (6) and HL-60 (7) cell lysate. Mouse IgG1 5B3 Ascites Hu E, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

STAT5B pTyr699 antibody

STAT5B Mouse IgG1 A4B9 Aff - Purified Hu E
0.5 mg / €480.00
  Acris Antibodies GmbH

STAT5B pTyr694 antibody

STAT5B Mouse IgG2b A2H6 Aff - Purified Hu E
0.5 mg / €480.00
  Acris Antibodies GmbH

STAT5B (N-term) antibody

Breast: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

STAT5B antibody

Immunohistochemistry analyzes of Stat5b antibody (AP20284PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

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