Stathmin-2 / STMN2 antibody

Principal name

Stathmin-2 / STMN2 antibody

Alternative names for Stathmin-2 / STMN2 antibody

Stathmin 2, SCG10, SCGN10, Superior cervical ganglion-10 protein

SwissProt ID

P21818 (Rat), P55821 (Mouse), Q90987 (Chick), Q93045 (Human)

Gene ID

11075 (STMN2), 84510 (Stmn2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Mky (Monkey), Por (Porcine), Rb (Rabbit), Eq (Equine), Hst (Hamster), Ze (Zebrafish)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Stathmin-2 / STMN2 antibody

STMN2 (Stathmin-2 or SCG10/Scgn10) belongs to stathmin family of proteins which are known to bind tubulin for acting as a sequestering agents and for promoting microtubule disassembly. STMN2 is a membrane-associated neurol protein expressed mainly during development and its expression correlates with neurite outgrowth. STMN2 possesses a unique N-termil domain that is critical for membrane binding, is responsible for STMN2 localization to the Golgi complex and is important in its targeting to growth cones. STMN2 localize to perinuclear cytoplasm, axons, and growth cones of developing neurons, and exists in soluble as well as membrane-bound forms. STMN2 interacts with ITMC2, as well as MAPK8, and when phosphorylated by MAPK8, it act as regulator of microtubule stability which controls neurite length in cortical neurons. Unlike other stathmins, STMN2 acts in two ways to promote microtubule dymics: it stabilizes microtubules at their plus end and promotes microtubule catastrophe at their minus end. In the developing brain, STMN2 negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Reduced STMN2 expression is associated with Down's syndrome and Alzheimer's disease.

General readings

Bahn S, Mimmack M, Ryan M, Caldwell MA, Jauniaux E, Starkey M, Svendsen CN, Emson P.
Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study.
Lancet. 2002 Jan 26;359(9303):310-5.
PMID: 11830198

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Stathmin-2 / STMN2 antibody

Western Blot: STMN2 Antibody [TA336784] - Analysis of endogenous STMN2 in mouse dorsal root ganglia (DRG) neurons.  A partial siRNA knockdown was used in the second lane.  TA336784 was used at a dilution of 1:1000.  Image courtesy of Dr. Jung Eun Shin. Rabbit Purified Bov, Hu, Ms, Rt C, FN, ICC/IF, WB
50 µl / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 (N-term) antibody

TA302781 staining (1µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

Sample (30 ug of whole cell lysate). A: A549 12% SDS PAGE. TA308308 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

Anti-STMN2 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Goat Purified Bov, Can, Hu, Ms, Rt E, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using STMN2/STMN3/STMN4 Antibody at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

Gel: 10+12%SDS-PAGE, Lysate: 30 µg, Lane: Human liver cancer tissue, Primary antibody: STMN2/STMN3/STMN4 Antibody at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2b L5/1 Supernatant Hu, Ms, Rt C, IP
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Stathmin-2 / STMN2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2b L5/1 Purified Hu, Ms, Rt C, IP
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Stathmin-2 / STMN2 (C-term) antibody

Western blot analysis of Stathmin-2 / STMN2 (C-term) Cat.-No AP54079PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the STMN2 antibody detected the STMN2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse IgM 3B12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Detection limit for recombinant GST tagged STMN2 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 1C6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse IgM 2B2 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse IgM 3E4 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Detection limit for recombinant GST tagged STMN2 is approximately 1ng/ml as a capture antibody. Mouse IgG 1D3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

STMN2 monoclonal antibody (M06), clone 2G11 Western Blot analysis of STMN2 expression in IMR-32 ( Cat # L008V1 ). Mouse IgG2b 2G11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Western Blot analysis of STMN2 expression in transfected 293T cell line by STMN2 monoclonal antibody (M07), clone 2G7.

Lane 1: STMN2 transfected lysate(20.8 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 2G7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

STMN2 monoclonal antibody (M15), clone 2E3. Western Blot analysis of STMN2 expression in human placenta. Mouse IgG2a 2E3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse IgG2b 1A7 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Stathmin-2 / STMN2 antibody

Stathmin-2 / STMN2 Mouse IgG2b 1A7 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

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