Stathmin-2 / STMN2 antibody

Principal name

Stathmin-2 / STMN2 antibody

Alternative names for Stathmin-2 / STMN2 antibody

Stathmin 2, SCG10, SCGN10, Superior cervical ganglion-10 protein

SwissProt ID

P21818 (Rat), P55821 (Mouse), Q90987 (Chick), Q93045 (Human)

Gene ID

11075 (STMN2), 84510 (Stmn2), 20257

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Functional assay (FN)

Background of Stathmin-2 / STMN2 antibody

STMN2 (Stathmin-2 or SCG10/Scgn10) belongs to stathmin family of proteins which are known to bind tubulin for acting as a sequestering agents and for promoting microtubule disassembly. STMN2 is a membrane-associated neurol protein expressed mainly during development and its expression correlates with neurite outgrowth. STMN2 possesses a unique N-termil domain that is critical for membrane binding, is responsible for STMN2 localization to the Golgi complex and is important in its targeting to growth cones. STMN2 localize to perinuclear cytoplasm, axons, and growth cones of developing neurons, and exists in soluble as well as membrane-bound forms. STMN2 interacts with ITMC2, as well as MAPK8, and when phosphorylated by MAPK8, it act as regulator of microtubule stability which controls neurite length in cortical neurons. Unlike other stathmins, STMN2 acts in two ways to promote microtubule dymics: it stabilizes microtubules at their plus end and promotes microtubule catastrophe at their minus end. In the developing brain, STMN2 negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Reduced STMN2 expression is associated with Down's syndrome and Alzheimer's disease.

General readings

Bahn S, Mimmack M, Ryan M, Caldwell MA, Jauniaux E, Starkey M, Svendsen CN, Emson P.
Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study.
Lancet. 2002 Jan 26;359(9303):310-5.
PMID: 11830198

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Stathmin-2 / STMN2 antibody

  Rabbit Polyclonal Stathmin-2/STMN2 Antibody  
Western Blot: STMN2 Antibody [TA336784] - Analysis of endogenous STMN2 in mouse dorsal root ganglia (DRG) neurons.  A partial siRNA knockdown was used in the second lane.  TA336784 was used at a dilution of 1:1000.  Image courtesy of Dr. Jung Eun Shin. Rabbit Purified Bov, Hu, Ms, Rt C, FN, ICC/IF, WB
50 µl / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 (N-term) antibody

  Goat Polyclonal Antibody against STMN2  
TA302781 staining (1µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

  Rabbit polyclonal antibody to STMN2 (stathmin-like 2)  
Sample (30 ug of whole cell lysate). A: A549 12% SDS PAGE. TA308308 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

  SCG10 / STMN2 Goat Polyclonal Antibody  
Anti-STMN2 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Goat Purified Bov, Can, Hu, Ms, Rt E, P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

  Rabbit Polyclonal Anti-STMN2/STMN3/STMN4 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using STMN2/STMN3/STMN4 Antibody at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

  Rabbit Polyclonal Anti-STMN2/STMN3/STMN4 Antibody  
Gel: 10+12%SDS-PAGE, Lysate: 30 µg, Lane: Human liver cancer tissue, Primary antibody: STMN2/STMN3/STMN4 Antibody at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2b L5/1 Supernatant Hu, Ms, Rt C, IP
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Stathmin-2 / STMN2 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2b L5/1 Purified Hu, Ms, Rt C, IP
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Stathmin-2 / STMN2 (C-term) antibody

Western blot analysis of Stathmin-2 / STMN2 (C-term) Cat.-No AP54079PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the STMN2 antibody detected the STMN2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

STMN2 - human gene knockout kit via CRISPR

STMN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STMN2 - human gene knockout kit via CRISPR

STMN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STMN2 - human gene knockout kit via CRISPR

STMN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STMN2 - human gene knockout kit via CRISPR

STMN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stmn2 - mouse gene knockout kit via CRISPR

Stmn2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Stmn2 - mouse gene knockout kit via CRISPR

Stmn2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stmn2 - mouse gene knockout kit via CRISPR

Stmn2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Stathmin-2 / STMN2

  Recombinant protein of human stathmin-like 2 (STMN2)  
Stathmin-2 / STMN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Stathmin-2 / STMN2 (39-179)

Stathmin-2 / STMN2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €1,500.00
  Acris Antibodies GmbH

Stathmin-2 / STMN2 (39-179)

Stathmin-2 / STMN2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €520.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Stmn2 (GFP-tagged) - Mouse stathmin-like 2 (Stmn2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Stmn2 (GFP-tagged) - Mouse stathmin-like 2 (Stmn2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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