Stathmin / STMN1 antibody

Principal name

Stathmin / STMN1 antibody

Alternative names for Stathmin / STMN1 antibody

LAP18, OP18, Phosphoprotein p19, pp19, Leukemia-associated phosphoprotein p18, Oncoprotein 18, Op18, pp17, Prosolin, Metablastin, Protein Pr22

SwissProt ID

P13668 (Rat), P16949 (Human), P31395 (Chick), P54227 (Mouse), Q3T0C7 (Bovin), Q4R712 (Macfa), Q6DUB7 (Pig)

Gene ID

3925 (STMN1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey), Por (Porcine), Can (Canine), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Stathmin / STMN1 antibody

Stathmin (oncoprotein 18, op18) is a ubiquitous cytosolic phosphoprotein with various regulatory functions in cell proliferation, differentiation signaling, and activation (1). In particular, stathmin is involved in the regulation of tubulin dynamics through inhibition of microtubule formation and/or microtubule depolymerization. Stathmin interacts with soulable tubulins (alpha,beta-tubulin) resulting in the formation of T2S complex which sequesters free tubulin, impeding tubulin formation (2). Stathmin activity is regulated through phosphorylation at Ser16, Ser25, Ser38 and Ser63 by various protein kinases (e.g. MAP-kinase, p34cdc2 kinase), weakening stathmin's affinity to tubulin (3). A mutation on stathmin can lead to excess build up of mitotic spindle and with possible consequence of unregulated cell cycles seen in cancer cells (4). Stathmin is also known as the generic member of a protein family which includes neural proteins SCG10, SCLIP and RB3/RB3'/RB3". All members in this family exhibits tubulin binding ability.

General readings

Miyashita H, Kanemura M, Yamazaki T, Abe M, Sato Y. . Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene.. Arterioscler Thromb Vasc Biol. 2004 May;24(5):878-84. Epub 2004 Mar 18. . PMID: 15031128

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Stathmin / STMN1 (C-term) antibody

TA303084 (1µg/ml) staining of Human Testes Lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu ICC/IF, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

Human tonsi stained with Stathmin Antibody Cat.-No AM11194PU (Clone SP49). Rabbit SP49 Purified Hu, Ms F, P, WB
0.5 ml / €520.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

Human tonsi stained with Stathmin Antibody Cat.-No AM11194PU (Clone SP49). Rabbit SP49 Purified Hu, Ms F, P, WB
1 ml / €750.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

Human tonsi stained with Stathmin Antibody Cat.-No AM11194PU (Clone SP49). Rabbit SP49 Purified Hu, Ms F, P, WB
0.1 ml / €290.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

AP15800PU Stathmin antibody staining of Human Breast Carcinoma. Rabbit Purified Hu P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

AP15800PU Stathmin antibody staining of Human Breast Carcinoma. Rabbit Purified Hu P, WB
1 ml / €520.00
  Acris Antibodies GmbH

Stathmin / STMN1 antibody

AP15800PU Stathmin antibody staining of Human Breast Carcinoma. Rabbit Purified Hu P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH

Stathmin / STMN1 (C-term) antibody

Western blot analysis of op18 in EL4 cell lysate with op18 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 (N-term) antibody

Western blot analysis of op18 in human brain tissue lysate with op18 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Western blot analysis of extracts from Jurkat cells untreated or treated with PMA (1ng/ml, 15min), using Stathmin 1 antibody (Lanes 1 and 2) and Stathmin 1 (phospho-Ser37) antibody (Lanes 3 and 4). Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Predicted band size: 17 kDa . Positive control: 293 and Hela cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 12%SDS-PAGE Lane1,2: 293 and Hela cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Western blot analysis of Stathmin 1 expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using STMN1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Hela cells were treated with 300 uM mimosine for 16 hrs, then placed in complete media (lane 1) or media containing 200 ng/ml nocodazole (lane 2) for an additional 18 hrs and cell extract prepared, resolved by electrophoresis, and transferred to nitrocellulose. Nitrocellulose blots were treated overnight with 100 U/ml calf intestinal phosphatase (CIP) (panel A), or not treated with CIP (panel B), and probed with anti-phosphorylated Stathmin/Op18 (Ser16), Poly6202. Rabbit IgG Poly6202 Purified Hu WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Western Blot: Stathmin 1 Antibody [TA336822] - EL4 cell lysate with op18 antibody at (A) 0.5, (B) 1 and © 2 ug/mL. Rabbit Purified Hu, Ms, Rt C, E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 antibody

Western blot analysis of Stathmin 1 expression in Jurkat cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Stathmin / STMN1 pSer24 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 antibody (AP02483PU-S; AP02483PU-N). Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Stathmin / STMN1 pSer24 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 antibody (AP02483PU-S; AP02483PU-N). Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €240.00
  Acris Antibodies GmbH

Stathmin / STMN1 pSer37 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1 antibody (AP02484PU-S; AP02484PU-N). Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

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