STEAP / STEAP1 antibody

Principal name

STEAP / STEAP1 antibody

Alternative names for STEAP / STEAP1 antibody

STEAP-1, Metalloreductase STEAP1, PRSS24, Six-transmembrane epithelial antigen of prostate 1

SwissProt ID

Q9CWR7 (Mouse), Q9GL50 (Pig), Q9UHE8 (Human)

Gene ID

26872 (STEAP1), 70358 (Steap1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of STEAP / STEAP1 antibody

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions.
Prostate cancer is the most frequently diagnosed cancer and is the second leading cause of cancer-related deaths in American men. Although the early serum detection of prostate-specific antigen (PSA) plays important roles in early diagnosis, it may not distinguish prostate cancer from benign diseases. Recently, a novel protein, which contains 339 amino acids, named STEAP (six transmembrane epithelial antigen of the prostate), was identified in advanced prostate cancer. STEAP is unique among the currently known prostate cancer markers because of its putative secondary structure, from which one may predict that it functions as a potential channel protein. STEAP is strongly expressed in advanced prostate cancer and some extent expression in other cancers, such as colon and ovarian cancer cell lines.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STEAP / STEAP1 (C-term) antibody

  Rabbit Polyclonal STEAP1 Antibody  
Western blot analysis of STEAP1 in human spleen tissue lysate with STEAP1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP / STEAP1 (Center) antibody

  Rabbit Polyclonal STEAP1 Antibody  
Western blot analysis of STEAP1 in human spleen tissue lysate with STEAP1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP / STEAP1 antibody

  Rabbit Polyclonal Anti-STEAP1 Antibody  
WB Suggested Anti-STEAP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

STEAP / STEAP1 antibody

Immunohistochemistry: Paraffin embedded sections of human breast cancer and prostate hyperplasia tissue were incubated with anti-human STEAP1 antibody Cat.-No AM09036PU (Clone J2D2) (1/50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Mouse IgG2b J2D2 Purified Hu, Rt E, ICC/IF, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

STEAP / STEAP1 antibody

Immunohistochemistry: Paraffin embedded sections of human breast cancer and prostate hyperplasia tissue were incubated with anti-human STEAP1 antibody Cat.-No AM09036PU (Clone J2D2) (1/50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Mouse IgG2b J2D2 Purified Hu, Rt E, ICC/IF, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

STEAP / STEAP1 (C-term) antibody

Formalin fixed, paraffin embedded human spleen stained with Rabbit anti Human STEAP1 (AP05708PU-N) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0) Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

STEAP / STEAP1 antibody

Lung, bronchiole: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

STEAP / STEAP1 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

STEAP1 - human gene knockout kit via CRISPR

STEAP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STEAP1 - human gene knockout kit via CRISPR

STEAP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STEAP1 - human gene knockout kit via CRISPR

STEAP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STEAP1 - human gene knockout kit via CRISPR

STEAP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap1 - mouse gene knockout kit via CRISPR

Steap1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Steap1 - mouse gene knockout kit via CRISPR

Steap1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap1 - mouse gene knockout kit via CRISPR

Steap1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap1 - mouse gene knockout kit via CRISPR

Steap1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

STEAP / STEAP1

  Recombinant protein of human six transmembrane epithelial antigen of the prostate 1 (STEAP1)  
STEAP / STEAP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

STEAP1 overexpression lysate

STEAP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, STEAP1 (mGFP-tagged) - Human six transmembrane epithelial antigen of the prostate 1 (STEAP1), 200 uL, >10^7 TU/mL

Lenti ORF particles, STEAP1 (mGFP-tagged) - Human six transmembrane epithelial antigen of the prostate 1 (STEAP1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, STEAP1 (Myc-DDK tagged) - Human six transmembrane epithelial antigen of the prostate 1 (STEAP1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, STEAP1 (Myc-DDK tagged) - Human six transmembrane epithelial antigen of the prostate 1 (STEAP1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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