STEAP3 / TSAP6 antibody

Principal name

STEAP3 / TSAP6 antibody

Alternative names for STEAP3 / TSAP6 antibody

STEAP-3, Metalloreductase STEAP3, pHyde, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6

SwissProt ID

Q5RKL5 (Rat), Q658P3 (Human), Q8CI59 (Mouse), Q8TDP3 (Human)

Gene ID

55240 (STEAP3), 68428 (Steap3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of STEAP3 / TSAP6 antibody

Caspases modulate apoptosis in various ways. Specifically, Caspase-3, a death protease, is instrumental in cleaving cellular proteins, dismantling the cell and forming apoptotic bodies. pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombint pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU145 tumors may be reduced significantly in vivo when nude mice are injected with recombint pHyde. pHyde also has a demonstrated growth inhibitory effect on human breast cancer cells. This suggests that pHyde may have a role in inhibiting different tumor types.

General readings

Sendamarai,A.K., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7410-7415

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STEAP3 / TSAP6 antibody

  Rabbit Polyclonal STEAP3 Antibody  
Western blot analysis of STEAP3 in rat liver tissue lysate with STEAP3 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

  Rabbit polyclonal anti-STEA3 antibody  
Western blot analysis of extracts from COLO205 cells, using STEA3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

  STEAP3 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using STEAP3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

  Rabbit Polyclonal Anti-STEAP3 Antibody  
WB Suggested Anti-STEAP3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

  Rabbit Polyclonal Anti-STEAP3 Antibody  
WB Suggested Anti-STEAP3 Antibody Titration: 5.0ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

  Rabbit Polyclonal Anti-STEA3 Antibody  
Western blot analysis on COLO205 cell lysate using STEA3 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

STEAP3 / TSAP6 (C-term) antibody

STEAP3 Antibody (C-term) (Cat. #AP54071PU-N) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the STEAP3 antibody detected the STEAP3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

STEAP3 / TSAP6 antibody

Immunofluorescence analysis of HeLa cells, using STEA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

STEAP3 / TSAP6 antibody

Immunofluorescence analysis of HeLa cells, using STEA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

STEAP3 - human gene knockout kit via CRISPR

STEAP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STEAP3 - human gene knockout kit via CRISPR

STEAP3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STEAP3 - human gene knockout kit via CRISPR

STEAP3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STEAP3 - human gene knockout kit via CRISPR

STEAP3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap3 - mouse gene knockout kit via CRISPR

Steap3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Steap3 - mouse gene knockout kit via CRISPR

Steap3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap3 - mouse gene knockout kit via CRISPR

Steap3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Steap3 - mouse gene knockout kit via CRISPR

Steap3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

STEAP3 / TSAP6 (transcript variant 3)

  Recombinant protein of human STEAP family member 3 (STEAP3), transcript variant 3  
STEAP3 / TSAP6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 (transcript variant 2)

  Recombinant protein of human STEAP family member 3 (STEAP3), transcript variant 2  
STEAP3 / TSAP6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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