STEAP3 / TSAP6 antibody

Principal name

STEAP3 / TSAP6 antibody

Alternative names for STEAP3 / TSAP6 antibody

STEAP-3, Metalloreductase STEAP3, pHyde, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6

SwissProt ID

Q5RKL5 (Rat), Q658P3 (Human), Q8CI59 (Mouse), Q8TDP3 (Human)

Gene ID

55240 (STEAP3), 6155240 (atpC)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of STEAP3 / TSAP6 antibody

Caspases modulate apoptosis in various ways. Specifically, Caspase-3, a death protease, is instrumental in cleaving cellular proteins, dismantling the cell and forming apoptotic bodies. pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombint pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU145 tumors may be reduced significantly in vivo when nude mice are injected with recombint pHyde. pHyde also has a demonstrated growth inhibitory effect on human breast cancer cells. This suggests that pHyde may have a role in inhibiting different tumor types.

General readings

Sendamarai,A.K., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7410-7415

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STEAP3 / TSAP6 antibody

Western blot analysis of STEAP3 in rat liver tissue lysate with STEAP3 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

Western blot analysis of extracts from COLO205 cells, using STEA3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

Western blot analysis of extracts of various cell lines, using STEAP3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

WB Suggested Anti-STEAP3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

WB Suggested Anti-STEAP3 Antibody Titration: 5.0ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

Western blot analysis on COLO205 cell lysate using STEA3 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STEAP3 / TSAP6 antibody

Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

STEAP3 / TSAP6 Control Peptide

STEAP3 / TSAP6
50 µg / €160.00
  Acris Antibodies GmbH

STEAP3 / TSAP6 (C-term) antibody

STEAP3 Antibody (C-term) (Cat. #AP54071PU-N) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the STEAP3 antibody detected the STEAP3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

STEAP3 / TSAP6 antibody

Immunohistochemistry of STEAP3 in mouse liver tissue with STEAP3 polyclonal antibody ( Cat # PAB13008 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

STEAP3 / TSAP6 antibody

Immunofluorescence analysis of HeLa cells, using STEA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

STEAP3 / TSAP6 antibody

Immunofluorescence analysis of HeLa cells, using STEA3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

STEAP3 / TSAP6 antibody

Human Liver; WB Suggested Anti-STEAP3 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Liver; STEAP3 antibody - C-terminal region (ARP43515_P050) in Human Liver cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

STEAP3 / TSAP6 antibody

Human HepG2; WB Suggested Anti-STEAP3 Antibody Titration: 5.0ug/ml. Positive Control: HepG2 cell lysate; STEAP3 antibody - N-terminal region (ARP43536_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

STEAP3 / TSAP6 antibody

Immunohistochemical analysis of STEAP3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

STEAP3 / TSAP6 antibody

Immunohistochemical analysis of STEAP3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

STEAP3 / TSAP6 antibody

Immunohistochemical analysis of STEAP3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

STEAP3 / TSAP6 antibody

STEAP3 / TSAP6 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €480.00
  Novus Biologicals Inc.

STEAP3 / TSAP6 antibody

STEAP3 / TSAP6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

STEAP3 / TSAP6 antibody

STEAP3 / TSAP6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €290.00
  Novus Biologicals Inc.

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