STK17B / DRAK2 antibody

Principal name

STK17B / DRAK2 antibody

Alternative names for STK17B / DRAK2 antibody

Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2

SwissProt ID

O94768 (Human), Q8BG48 (Mouse), Q91XS8 (Rat)

Gene ID

9262 (STK17B), 98267 (Stk17b)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of STK17B / DRAK2 antibody

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP,are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain anN-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

General readings

Friedrich ML, Cui M, Hernandez JB, Weist BM, Andersen HM, Zhang X, Huang L, Walsh CM: Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. J Biol Chem. 2007 Feb 282 (7): 4573-84. PMID: 17182616

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STK17B / DRAK2 antibody

  Goat Anti-DRAK2 Antibody  
TA305652 (1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 (C-term) antibody

  Rabbit Polyclonal DRAK2 Antibody  
Western blot analysis of DRAK2 in Jurkat (1,3) and Raji (2,4) cell lysate in the absence (1,2) or presence (3,4) of blocking peptide with DRAK2 antibody at 1:500 dilution. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 antibody

  Rabbit polyclonal anti-STK17B antibody  
Western blot analysis of extracts from mouse brain cells, using STK17B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 antibody

  Rabbit Polyclonal anti-DAPK2 Antibody  
Human Breast Carcinoma stained with anti-DAPK2 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, Cortex. Rabbit Purified Hu ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

STK17B / DRAK2 (C-term) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

STK17B / DRAK2 (C-term) antibody

STK17B Antibody (C-term) (Cat. #AP54074PU-N) western blot analysis in A549 cell line lysates (35µg/lane).This demonstrates the STK17B antibody detected the STK17B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

STK17B - human gene knockout kit via CRISPR

STK17B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STK17B - human gene knockout kit via CRISPR

STK17B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STK17B - human gene knockout kit via CRISPR

STK17B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STK17B - human gene knockout kit via CRISPR

STK17B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

STK17B / DRAK2

  Recombinant protein of human serine/threonine kinase 17b (STK17B)  
STK17B / DRAK2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

STK17B / DRAK2 (1-372, His-tag)

STK17B / DRAK2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

STK17B / DRAK2 (1-372, His-tag)

STK17B / DRAK2 Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, STK17B (mGFP-tagged) - Human serine/threonine kinase 17b (STK17B), 200 uL, >10^7 TU/mL

Lenti ORF particles, STK17B (mGFP-tagged) - Human serine/threonine kinase 17b (STK17B), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, STK17B (Myc-DDK tagged) - Human serine/threonine kinase 17b (STK17B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, STK17B (Myc-DDK tagged) - Human serine/threonine kinase 17b (STK17B) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Stk17b (GFP-tagged) - Mouse serine/threonine kinase 17b (apoptosis-inducing) (Stk17b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Stk17b (GFP-tagged) - Mouse serine/threonine kinase 17b (apoptosis-inducing) (Stk17b), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Stk17b (Myc-DDK-tagged) - Mouse serine/threonine kinase 17b (apoptosis-inducing) (Stk17b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Stk17b (Myc-DDK-tagged) - Mouse serine/threonine kinase 17b (apoptosis-inducing) (Stk17b), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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