STK17B / DRAK2 antibody

Principal name

STK17B / DRAK2 antibody

Alternative names for STK17B / DRAK2 antibody

Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2

SwissProt ID

O94768 (Human), Q8BG48 (Mouse), Q91XS8 (Rat)

Gene ID

9262 (STK17B), 2692622 (aadR)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Bov (Bovine), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of STK17B / DRAK2 antibody

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP,are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain anN-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

General readings

Friedrich ML, Cui M, Hernandez JB, Weist BM, Andersen HM, Zhang X, Huang L, Walsh CM: Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. J Biol Chem. 2007 Feb 282 (7): 4573-84. PMID: 17182616

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STK17B / DRAK2 antibody

Immunoperoxidase of monoclonal antibody to STK17B on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Mouse IgG2b 2C3 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STK17B / DRAK2 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

STK17B / DRAK2 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

STK17B / DRAK2 antibody

Human breast ca stained with Anti-DRAK2 Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

STK17B / DRAK2 antibody

TA305652 (1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 (C-term) antibody

Western blot analysis of DRAK2 in Jurkat (1,3) and Raji (2,4) cell lysate in the absence (1,2) or presence (3,4) of blocking peptide with DRAK2 antibody at 1:500 dilution. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 antibody

Western blot analysis of extracts from mouse brain cells, using STK17B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STK17B / DRAK2 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, Cortex. Rabbit Purified Hu ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

STK17B / DRAK2 Control Peptide

STK17B / DRAK2
50 µg / €160.00
  Acris Antibodies GmbH

STK17B / DRAK2 (C-term) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

STK17B / DRAK2 (C-term) antibody

STK17B Antibody (C-term) (Cat. #AP54074PU-N) western blot analysis in A549 cell line lysates (35µg/lane).This demonstrates the STK17B antibody detected the STK17B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

STK17B / DRAK2 antibody

STK17B / DRAK2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

STK17B / DRAK2 antibody

Western blot analysis using STK17B polyclonal antibody at 1 µg/ml on Jurkat (lane 1 and 2) and Raji (lane 3 and 4) cell lysates in the absense (lanes 1 and 2) and presense (lanes 3 and 4) of blocking peptide. Rabbit Hu WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

STK17B / DRAK2 antibody

Immunohistochemical staining of STK17B on formalin fixed, paraffin embedded human breast ca with STK17B polyclonal antibody. Rabbit Hu P
0.1 ml / €390.00
  Abnova Taiwan Corp.

STK17B / DRAK2 antibody

Immunohistochemical analysis of STK17B staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

STK17B / DRAK2 antibody

Immunohistochemical analysis of STK17B staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

STK17B / DRAK2 antibody

Immunohistochemical analysis of STK17B staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

STK17B / DRAK2 antibody

Western Blot: DRAK2 Antibody [NB100-56695] - Western blot analysis of 30 ug of total cell lysate from Raji cells with anti-DRAK2 NB100-56695 at 3 ug/ml dilution. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €320.00
  Novus Biologicals Inc.

STK17B / DRAK2 antibody

STK17B / DRAK2 Goat Aff - Purified Can, Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

STK17B / DRAK2 antibody

STK17B / DRAK2 Rabbit Purified Hu E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

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