STK4 antibody

Principal name

STK4 antibody

Alternative names for STK4 antibody

Serine/threonine-protein kinase 4, MST1, STE20-like kinase MST1, MST-1, STE20-like kinase MST1, Mammalian STE20-like protein kinase 1, Serine/threonine-protein kinase Krs-2

SwissProt ID

Q13043 (Human), Q5E9L6 (Bovin), Q5ZJK4 (Chick), Q9JI11 (Mouse)

Gene ID

6789 (STK4), 58231 (Stk4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Dot blot (Dot)

Background of STK4 antibody

The human serine/threonine kinase, mammalian STE20-like kinase (MST), is considerably homologous to the budding yeast kinases, SPS1 and STE20, throughout their kinase domains. When stably expressed in HeLa cells, MST highly sensitizes the cells to death receptor-mediated apoptosis by accelerating caspase-3 activation. These findings suggest that MST1 and MST2 play a role in apoptosis both upstream and downstream of caspase activation (1). MST1 is cleaved and activated by caspases during apoptosis and is capable of inducing apoptotic morphological changes such as chromatin condensation upon overexpression (2). Mammalian Sterile 20-Like 2 (Mst2) is most similar to the previously identified Mst1 protein kinase (78% identity, 88% similarity). Northern analysis indicates that MST2 mRNA is expressed at high levels in adult kidney, skeletal and placental tissues and at very low levels in adult heart, lung, liver and brain tissues. An in-vitro kinase assay indicates that Mst2 can phosphorylate an exogenous substrate, as well as itself, and phospho-amino-acid analysis indicates that it is a serine/threonine protein kinase (3)

General readings

1. Lee KK, et al. J. Biol Chem. 276(22):19276-85, 2001.
2. Ura S, et al. Proc Natl Acad Sci USA 98(18):10148-53,
2001
3. Cheung WL, et al. Cell. 113(4):507-17, 2003.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

STK4 antibody

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308695 diluted at 1:2000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

STK4 antibody

STK4 polyclonal antibody (A01), Lot # 060707JCS1. Western Blot analysis of STK4 expression in NIH/3T3. Mouse Serum Hu, Ms, Rt E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

STK4 antibody

Immunoperoxidase of monoclonal antibody to STK4 on formalin-fixed paraffin-embedded human stomach carcinoma tissue. [antibody concentration 5ug/ml] Mouse IgG1 1D7-8A10 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STK4 antibody

Immunofluorescence of monoclonal antibody to STK4 on HeLa cell. [antibody concentration 25 ug/ml] Mouse IgG2a 4F4 Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

STK4 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

STK4 antibody

Western blot analysis of STK4 in 15 µgs of Jurkat cell lysate using STK4 polyclonal antibody ( Cat # PAB0373 ) at 1 µg/ml. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

STK4 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the STK4 polyclonal antibody ( Cat # PAB2295 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

STK4 antibody

Western blot analysis of STK4 expression in Jurkat cell lysate. Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

STK4 antibody

Immunohistochemistry: Mst1 Antibody (EP1465Y) [NB110-57228] - Immunohistochemical staining of paraffin-embedded human urinary bladder using anti-Mst1 (cat. #110-57228). Rabbit IgG EP1465Y Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

STK4 antibody

Immunohistochemistry: STK4 Antibody [NBP1-31233] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using STK4 antibody at 1:500 dilution. Rabbit IgG Hu Dot, ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

STK4 antibody

Immunohistochemistry-Paraffin: STK4 Antibody [NBP1-82865] - Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

STK4

STK4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

STK4

STK4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

STK4

STK4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

STK4

STK4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

STK4

STK4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

STK4

STK4 Human
5 µg / €830.00
  Abnova Taiwan Corp.

STK4

STK4 Human
0.1 mg / €1,260.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

Human MST1 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Mouse MST1 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

20 Item(s)

per page
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