stxB / Shiga-like toxin 1 subunit B antibody

Principal name

stxB / Shiga-like toxin 1 subunit B antibody

Alternative names for stxB / Shiga-like toxin 1 subunit B antibody

sltB, Verocytotoxin 1 subunit B, Verotoxin 1 subunit B

SwissProt ID

P69178, P69179, Q32GM0, Q779K3, Q7BQ98

Gene ID

916677

Available reactivities

Bac (Bacteria)

Available hosts

Mouse

Available applications

Enzyme Immunoassay (E), Neutralisation (NEUT), Functional assay (FN), Western blot / Immunoblot (WB)

Background of stxB / Shiga-like toxin 1 subunit B antibody

Shiga-like toxins (SLTs), are also called Verotoxins. Enterohemorrhagic Escherichia coli (EHEC) strains which are primarily of serotypes 0157:H7, 026:H11 and O111:H8 have been incriminated as etiologic agents of hemorrhagic colitis and Hemolytic-uremic syndrome, a generalized disease characterized by acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia. There are several distinct E.coli SLTs. SLT-I and SLT-II are produced by EHEC.
SLT-I and Shiga toxin share >99% deduced amino acid sequence homology, whereas SLT-I and SLT-II share about 60% deduced amino acid sequence homology. SLT-I and SLT-II are antigenically distinct.The protein structure of the toxin consists of two domains: the A polypeptide that inhibits protein synthesis by targeting ribosomes, and the B polypeptide pentamer that binds to the eukaryotic cell receptor globotriaosylceramide (Gb3) leading to receptor-mediated endocytosis.

1 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

stxB / Shiga-like toxin 1 subunit B antibody

stxB / Shiga-like toxin 1 subunit B Mouse IgG1 13C4 Purified E, FN, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

1 Item(s)

per page
  • LinkedIn