Sulfiredoxin-1 antibody

Principal name

Sulfiredoxin-1 antibody

Alternative names for Sulfiredoxin-1 antibody

Sulfiredoxin1, SRXN1, C20orf139, SRX, EC=1.8.98.2

SwissProt ID

Q9BYN0 (Human), Q9D975 (Mouse)

Gene ID

140809 (SRXN1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine)

Available hosts

Goat, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P)

Background of Sulfiredoxin-1 antibody

Sulfiredoxin, also designated Sulfiredoxin-1 and chromosome 20 open reading frame 139 (C20orf139), is a cytoplasmic antioxidant protein involved in signaling through catalytic reduction of oxidative modifications. It regulates peroxiredoxins (PRXs), a family of proteins that reduce hydroperoxides, by reducing the conserved cysteine from sulfinic to sulfenic acid. This impacts the role of PRX in the reduction of other downstream transcription factors and kinase signaling pathways. The Sulfiredoxin protein specifically acts on the PRDX1, PRDX2, PRDX3 and PRDX4 peroxiredoxins, but not on PRDX5 or PRDX6. Sulfiredoxin acts as a phosphotransferase and an athioltransferase and is widely expressed, with highest levels detected in lung, spleen, kidney and thymus tissues.

General readings

Jönsson TJ, Johnson LC, Lowther WT.
Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace.
Nature. 2008 Jan 3;451(7174):98-101.
PMID: 18172504

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Sulfiredoxin-1 antibody

TA305893 (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Sulfiredoxin-1 antibody

Sulfiredoxin-1 Goat IgG Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SRXN1 overexpression lysate

SRXN1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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