SUMF1 / FGE antibody

Principal name

SUMF1 / FGE antibody

Alternative names for SUMF1 / FGE antibody

Sulfatase-modifying factor 1, C-alpha-formylglycine-generating enzyme 1

SwissProt ID

Q0P5L5 (Bovin), Q8NBK3 (Human), Q8R0F3 (Mouse)

Gene ID

285362 (SUMF1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of SUMF1 / FGE antibody

SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.

General readings

Oshikawa M, Usami R, Kato S.
Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19.
Molecular vision 2009 15 : 482-94.
PMID: 19262745

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SUMF1 / FGE antibody

(1ug/ml) staining of Mouse Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SUMF1 / FGE antibody

Host: Rabbit; Target Name: SUMF1; Sample Tissue: PANC1 Whole cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SUMF1 / FGE (C-term) antibody

SUMF1 Antibody (C-Term) (Cat. #AP54107PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SUMF1 Antibody (C-Term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SUMF1 / FGE antibody

SUMF1 / FGE Goat Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SUMF1 / FGE

SUMF1 / FGE Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

SUMF1 / FGE

SUMF1 / FGE Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

SUMF1 / FGE (91-374, His-tag)

SUMF1 / FGE Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

SUMF1 / FGE (91-374, His-tag)

SUMF1 / FGE Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

SUMF1 / FGE

SUMF1 / FGE Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

SUMF1 / FGE

SUMF1 / FGE Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

SUMF1 / FGE

SUMF1 / FGE Human
50 µg / €380.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SUMF1 overexpression lysate

SUMF1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SUMF1 overexpression lysate

SUMF1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SUMF1 overexpression lysate

SUMF1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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