Superoxide Dismutase 3 / SOD3 antibody

Principal name

Superoxide Dismutase 3 / SOD3 antibody

Alternative names for Superoxide Dismutase 3 / SOD3 antibody

SOD-3, EC-SOD, Extracellular superoxide dismutase [Cu-Zn]

SwissProt ID

O09164 (Mouse), P08294 (Human), P34461 (Caeel), P41975 (Rabit), Q08420 (Rat)

Gene ID

6649 (SOD3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutases (SODs) are a unique family of metalloproteins that catalyze the dismutation of superoxide anion radicals (O2-) to oxygen (O2) and hydrogen peroxide (H2O2) O2- + O2- + 2H+ => H2O2 + O2 SOD is ubiquitous in oxygen metabolizing cells protecting these cells against direct and indirect oxygen-mediated free radical damage. Four types of SOD have been defined on the basis of distinctions in their metal cofactors and distribution: Manganese (MnSOD) principally located in the matrix of mitochondria of all aerobes, copper/zinc (Cu/ZnSOD) mainly present in the cytoplasm of eukaryotic cells, iron (FeSOD), predominantly in the cytosol, chloropasts or mitochondria of prokaryotes as well as extracellular (ECSOD), which is found in the extracellular fluids or membrane associated in mammals. The properties of Cu/Zn superoxide dismutase are quite different from those of the manganese or iron enzymes. Induction of Cu/ZnSOD expression resulting in elevated levels of Cu/ZnSOD in human body fluids is of diagnostic value for measuring the activity of different diseases: Nephropathies Cu/ZnSOD determination provides a tool for early diagnosis of nephropathies. Monitoring of therapeutic treatments Cu/ZnSOD is a useful therapeutic tool in the treatment of chronic inflammation e.g. rheumatoid arthritis or of the ischemic myocardium in the phase of reperfusion. Due to the short half-life of SOD injected into the blood circulation, a rapid assay is necessary for monitoring SOD levels. Trisomy 21 (Down's Syndrome) In cases with Down's Syndrome an additional part of chromosome 21 is present in the genome of the patient as a structural chromosome aberration. The Cu/ZnSOD gene is localized on chromosome 21, closely associated with the gene complex responsible for the phenotype of Down's Syndrome. A gene-dosage effect for Cu/ZnSOD in Down's Syndrome providing a diagnostic marker for this syndrome has been described. a) Patients with Down's Syndrome have significantly elevated serum and urine levels of Cu/ZnSOD. b) Prenatal diagnosis of Down's Syndrome: Cu/ZnSOD levels are quantitated from erythrocytes of fetal umbilical vein blood and related to the number of cells, the content of haemoglobin and to the haematocrit. In case of Trisomy 21 the significantly elevated levels of Cu/ZnSOD are determined.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Superoxide Dismutase 3 / SOD3 antibody

ICC staining of human cartilage samples using the antibody Mouse 4G11G6 Purified Hu, Ms, Rt C, E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Superoxide Dismutase 3 / SOD3 antibody

ICC staining of human cartilage samples using the antibody Mouse IgG1 4G11G6 Purified Hu, Ms, Rt C, E, ICC/IF, WB
25 µg / €230.00
  Acris Antibodies GmbH

Superoxide Dismutase 3 / SOD3 (N-term) antibody

Western blot analysis of SOD3 Antibody (N-term) (AP17757PU-N) in K562 cell line lysates (35ug/lane). SOD3 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Superoxide Dismutase 3 / SOD3 antibody

Detection limit for recombinant GST tagged SOD3 is approximately 10ng/ml as a capture antibody. Mouse IgG 5C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Superoxide Dismutase 3 / SOD3 antibody

Immunoblot analysis of cell lysates. Lane 1 : Bosc 23 cell lysate, lane 2 : Bosc 23 cell lysate transfected with Myc-His-SOD3 and lane 3 : Bosc 23 cell lysate transfected with Myc-His-Gpx3. Mouse IgG2b 1H12 Hu C, E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 Antibody (4G11G6) [NBP1-22417] -  Human cartilage, ICC Left control, middle young, right cartilage with osterarthritis Mouse IgG1 4G11G6 Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Rabbit IgG Hu C, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Mouse IgG2b 1H12 Hu IP, WB
0.1 mg / €530.00
  Novus Biologicals Inc.

Superoxide Dismutase 3 / SOD3 antibody

Superoxide Dismutase 3 / SOD3 Rabbit IgG Purified Ms C, P, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Superoxide Dismutase 3 / SOD3

Superoxide Dismutase 3 / SOD3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Superoxide Dismutase 3 / SOD3

Superoxide Dismutase 3 / SOD3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Superoxide Dismutase 3 / SOD3

Superoxide Dismutase 3 / SOD3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

SOD3 (Human) ELISA kit

SOD3 (Human) ELISA kit  
1 kit / €590.00
  Abnova Taiwan Corp.

Superoxide Dismutase 3 ELISA Kit

Superoxide Dismutase 3 ELISA Kit  
96 Tests / €620.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SOD3 overexpression lysate

SOD3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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