SUV420H1 / KMT5B antibody

Principal name

SUV420H1 / KMT5B antibody

Alternative names for SUV420H1 / KMT5B antibody

Lysine N-methyltransferase 5B, Histone-lysine N-methyltransferase SUV420H1, Suppressor of variegation 4-20 homolog 1

SwissProt ID

P0C2N5 (Rat), Q29RP8 (Bovin), Q3U8K7 (Mouse), Q4FZB7 (Human), Q5U3H2 (Danre), Q8BZ24 (Mouse), Q9H2K3 (Human)

Gene ID

51111 (SUV420H1), 225888 (Suv420h1)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of SUV420H1 / KMT5B antibody

SUV420H1 (Histone-lysine N-methyltransferase 5B, KMT5B) is a histone methyltransferase that specifically di- and trimethlyates lysine 20 of H4 (H4 K20Me3), an epigenetic mark of transcriptiol repression. This mark, along with trimethylation of histone 3 lysine 9 (H3 K9me3) and monomethylation of H3 lysine 27 (H3 K27me1), define genomic regions of constitutive heterochromatin that are poor in activated genes. This enzyme is essential for development, with Suv420h1 knockout mice proving lethal peritally and showing overall growth retardation. The RB1 family of proteins have been shown to interact with, and target, KMT5B to histones, ebling the enzyme to function.

General readings

Strausberg,R.L., et al., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903

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  2. Highly Validated (2)

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SUV420H1 / KMT5B antibody

WB Suggested Anti-SUV420H1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Placenta Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B (Isoform 3) antibody

Human Skin; Rabbit Anti-SUV420H1 Antibody. Catalog Number: ARP34567. Paraffin Embedded Tissue: Human Skin. Cellular Data: Squamous epithelial cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; SUV420H1 antibody - middle region (ARP34567_P050) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

SUV420H1 / KMT5B antibody

WB Suggested Anti-SUV420H1 Antibody; Titration: 1.25 ug/ml; Positive Control: Jurkat Whole Cell Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B antibody

Immunohistochemistry: SUV420h1 Antibody [TA336868] - IHC analysis of SUV420h1 in mouse epidermis using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B antibody

Immunohistochemistry: SUV420h1 Antibody [TA336869] - IHC analysis of SUV420h1 in mouse epidermis using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B antibody

WB Suggested Anti-SUV420H1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B antibody

WB Suggested Anti-Suv420h1 Antibody; Titration: 1.0 ug/ml; Positive Control: Mouse Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze ChIP, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SUV420H1 / KMT5B (C-term) antibody

SUV4-20H1 Antibody (C-term) (Cat. AP54114PU-N) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the SUV4-20H1 antibody detected the SUV4-20H1 protein (arrow). Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

SUV420H1 / KMT5B antibody

Suv420H1 antibody (AP55013SU-N) recognized ectopicaly expressed small isoform of human Suv420H1 protein Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

SUV420H1 / KMT5B antibody

Human Skin; Rabbit Anti-SUV420H1 Antibody Catalog Number: ARP34567 Paraffin Embedded Tissue: Human Skin Cellular Data: Squamous epithelial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X; SUV420H1 antibody - C-terminal region (ARP34567_T100) in Human Skin cells using Immunohistochemistry Rabbit IgG Purified African clawed frog, Chk, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

SUV420H1 / KMT5B antibody

Human Lung; WB Suggested Anti-SUV420H1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; SUV420H1 antibody - middle region (ARP34744_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SUV420H1 / KMT5B antibody

Western Blot: SUV420h1 Antibody [NBP1-49611] - HEK293T cells expressing SUV420h1 Rabbit Purified Hu E, P, WB
0.1 ml / €320.00
  Novus Biologicals Inc.

SUV420H1 / KMT5B antibody

SUV420H1 / KMT5B Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

SUV420H1 / KMT5B antibody

Immunohistochemistry-Paraffin: SUV420h1 Antibody [NBP1-92461] Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SUV420H1 / KMT5B

SUV420H1 / KMT5B Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SUV420H1 overexpression lysate

SUV420H1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

SUV420H1 overexpression lysate

SUV420H1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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