SYCP3 / SCP3 antibody

Principal name

SYCP3 / SCP3 antibody

Alternative names for SYCP3 / SCP3 antibody

SCP-3, Synaptonemal complex protein 3

SwissProt ID

P70281 (Mouse), Q3T0E2 (Bovin), Q63520 (Rat), Q8IZU3 (Human)

Gene ID

50511 (SYCP3), 20962 (Sycp3), 25561

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of SYCP3 / SCP3 antibody

SCP3 (Syptonemal complex protein 3) is a D-binding nuclear protein that belongs to XLR/SYCP3 family and is an essential structural component of the transverse filaments of syptonemal complexes formed between homologous chromosomes during meiotic prophase. Syptonemal complex develops during prophase of first meiosis, wherein it allows the sypse as well as recombition between materl - paterl chromosome, and SCP3 is essential to hold cohesin complex between homologous chromosomes, which avoid premature segregation thereby preventing aneuploidies. SCP3 is involved in phosphorylation of HORMAD1 and HORMAD2. It is essential to development of testis (where it is primarily localized) and defective SCP3 may leads to spermatogenic failure type 4 (SPGF4). SCP3 deificient mouse depicts high numbers of aneuploidies in oocytes and offspring. SCP3 is also expressed in certain maligncies including human acute lymphatic leukemias, cervical cancer cells, lung cancer cells etc.

General readings

Bukovsky,A., (2008) Cell Cycle 7 (5), 683-686

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SYCP3 / SCP3 antibody

  Mouse Monoclonal SCP3/SYCP3 Antibody (6F9C5)  
Western Blot: SCP3 Antibody (6F9C5) [TA336946] - Western blot analysis of human testis tissue (A), human ovary tissue (B), mouse testis tissue ©, and mouse ovary tissue (D) using SCP3 antibody at 2 ug/ml. Mouse IgG1 6F9C5 Purified Hu C, E, F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SYCP3 / SCP3 antibody

  Rabbit Polyclonal SCP3 Antibody  
Western Blot: SCP3 Antibody - Western blot analysis of SCP3 in mouse testis protein using anti-SCP3. Rabbit Purified Hu, Ms, Por, Rt C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SYCP3 / SCP3 antibody

  Rabbit Polyclonal Anti-SYCP3 Antibody - N-terminal region  
WB Suggested Anti-SYCP3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

SYCP3 / SCP3 antibody

  Rabbit Polyclonal Anti-SYCP3 Antibody  
SYCP3 / SCP3 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI3D6 (formerly 3D6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI3D6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI2E3 (formerly 2E3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI2E3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI5G3 (formerly 5G3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI5G3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI1B11 (formerly 1B11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI1B11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI2F4 (formerly 2F4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI2F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI3H5 (formerly 3H5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI3H5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 antibody

  SYCP3 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYCP3 (RC209340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYCP3. Mouse IgG1 OTI3B8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

SYCP3 / SCP3 (C-term) antibody

SYCP3 / SCP3 Rabbit IgG Aff - Purified Ms ICC/IF, P
0.1 ml / €360.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

SYCP3 - human gene knockout kit via CRISPR

SYCP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SYCP3 - human gene knockout kit via CRISPR

SYCP3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sycp3 - mouse gene knockout kit via CRISPR

Sycp3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Sycp3 - mouse gene knockout kit via CRISPR

Sycp3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sycp3 - mouse gene knockout kit via CRISPR

Sycp3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Sycp3 - mouse gene knockout kit via CRISPR

Sycp3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

SYCP3 / SCP3

  Recombinant protein of human synaptonemal complex protein 3 (SYCP3)  
SYCP3 / SCP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SYCP3 (mGFP-tagged) - Human synaptonemal complex protein 3 (SYCP3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SYCP3 (mGFP-tagged) - Human synaptonemal complex protein 3 (SYCP3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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