SYF1 / XAB2 antibody

Principal name

SYF1 / XAB2 antibody

Alternative names for SYF1 / XAB2 antibody

HCNP, KIAA1177, PP3898, Pre-mRNA-splicing factor SYF1, XPA-binding protein 2

SwissProt ID

Q99PK0 (Rat), Q9DCD2 (Mouse), Q9HCS7 (Human)

Gene ID

56949 (XAB2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Dros (Drosophila), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of SYF1 / XAB2 antibody

Tim50 is a component of the yeast Tim23 import machinery, which mediates translocation of presequence containing proteins across the mitochondrial inner membrane. By searching sequence databases, open reading frames encoding proteins with similarity to Tim50 and with a putative mitochondrial presequence were identified in the genomes of evolutionarily distant organisms, including human. Tim50 was found to interact with the N terminal intermembrane space domain of Tim23. Functional defects of Tim50 either by depletion of the protein or addition of anti Tim50 antibodies blocked the protein translocation across the inner membrane. A translocation intermediate accumulated at the translocator of the outer mitochondrial membrane (TOM) complex was cross linked to Tim50. Thus it can be concluded that Tim50, in cooperation with Tim23, facilitates transfer of the translocating protein from the TOM complex to the Tim23 complex.

General readings

Nakatsu Y et al. XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. J Biol Chem 275:34931-7 (2000). PubMed PMID: 10944529

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SYF1 / XAB2 antibody

Immunoperoxidase of monoclonal antibody to XAB2 on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml] Mouse IgG2b 1D1-1A9 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

SYF1 / XAB2 (C-term) antibody

TA302713 staining (0.3µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SYF1 / XAB2 antibody

WB Suggested Anti-XAB2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: PANC1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

SYF1 / XAB2 antibody

WB Suggested Anti-XAB2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

SYF1 / XAB2 antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SYF1 / XAB2 (C-term) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

SYF1 / XAB2 antibody

SYF1 / XAB2 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

SYF1 / XAB2 antibody

Western Blot analysis of XAB2 expression in transfected 293T cell line (H00056949-T01) by XAB2 MaxPab polyclonal antibody.

Lane1:XAB2 transfected lysate(94.05 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

SYF1 / XAB2 antibody

XAB2 polyclonal antibody ( Cat # PAB6025 ) staining ( 0.3 µg/ml ) of A-431 lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

SYF1 / XAB2 antibody

Human PANC1; WB Suggested Anti-XAB2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: PANC1 cell lysate; XAB2 antibody - N-terminal region (ARP50636_P050) in Human PANC1 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SYF1 / XAB2 antibody

Human MCF-7; WB Suggested Anti-XAB2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: MCF7 cell lysate; XAB2 antibody - C-terminal region (ARP50637_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Bov, Can, Dros, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

SYF1 / XAB2 antibody

SYF1 / XAB2 Rabbit Aff - Purified Hu WB
0.1 mg / €320.00
  Novus Biologicals Inc.

SYF1 / XAB2 antibody

NB 100-794 staining (0.3µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

XAB2 293T Cell Transient Overexpression Lysate(Denatured)

XAB2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

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