Synapsin-1 antibody

Principal name

Synapsin-1 antibody

Alternative names for Synapsin-1 antibody

Synapsin I, Brain protein 4.1, SYN1

SwissProt ID

O62732 (Canfa), O88935 (Mouse), P09951 (Rat), P17599 (Bovin), P17600 (Human)

Gene ID

6853 (SYN1), 24949 (Syn1), 281510, 20964

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Xen (Xenopus), Ze (Zebrafish), Can (Canine), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Dot blot (Dot)

Selected product citations ‐ of AP02514PU-S

1. Emhoff, R. The Role of Neuropeptide-Y in Conveying the Degree of Glycemic Challenges in the Rat Paraventricular Nucleus of the Hypothalamus. Thesis 2016. http://dornsife.usc.edu/assets/sites/753/docs/Past_Students_with_Honors/2016_Honor_Thesis/Ryan_Emhoff.pdf

Background of Synapsin-1 antibody

Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989; Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002). Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I (Czernik et al., 1987). Phosphorylation of this site is thought to regulate synaptic vesicle function and neurite outgrowth (Kao et al., 2002).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synapsin-1 antibody

  Rabbit Anti-Synapsin I Antibody  
Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein. Rabbit IgG Aff - Purified Hu, Ms, Rt C, ICC/IF, IP, WB
10 µg / €325.00
  OriGene Technologies, Inc.

Synapsin-1 pSer9 antibody

Cultured mouse caudate neurons showing synapsin I when phosphorylated at Ser9 Rabbit IgG Aff - Purified Bov, Hu, Ms, Rt, Xen, Ze C, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

Synapsin-1 pSer62/67 antibody

Western blot of Rat cortex lysate showing specific immunolabeling of the ~78k Synapsin I phosphorylated at Ser62/67 (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown). Rabbit IgG Aff - Purified Bov, Ms, Rt Dot, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

Synapsin-1 pSer603 antibody

Figure 1. Western blot of rat cortex lysate showing specific immunolabeling of the ~78k Synapsin I phosphorylated at Ser603 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser603 synapsin I antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase. Rabbit IgG Aff - Purified Bov, Hu, Ms, Rt, Xen, Ze WB
0.1 ml / €380.00
  Acris Antibodies GmbH

Synapsin-1 antibody

  Rabbit Anti-Synapsin I Antibody  
Western blot of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~78k synapsin I doublet protein. Rabbit IgG Serum Hu, Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

Synapsin-1 antibody

  Rabbit Anti-Synapsin I (Ser9) Antibody (Phospho-Specific)  
Western blot of rat cortex lysate showing specific immunolabeling of the ~78k synapsin I phosphorylated at Ser9 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser9 synapsin I antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase. Rabbit IgG Purified Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synapsin-1 antibody

  Rabbit polyclonal synapsin (Ser9) antibody(Phospho-specific)  
Synapsin-1 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synapsin-1 antibody

  Anti-SYN1 (Phospho-Ser9) Rabbit Polyclonal Antibody  
Predicted band size: 74 kDa . Positive control: Mouse Brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: Mouse Brain tissue Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synapsin-1 antibody

  Rabbit Polyclonal Synapsin Antibody  
Western blot analysis of Synapsin expression in PMA treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synapsin-1 antibody

  Rabbit Polyclonal Anti-SYN1 Antibody  
Synapsin-1 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synapsin-1 pSer9 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using Synapsin pSer9 antibody Cat.-No AP02514PU (Red). Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Synapsin-1 pSer9 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using Synapsin pSer9 antibody Cat.-No AP02514PU (Red). Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µl / €240.00
  Acris Antibodies GmbH

Synapsin-1 antibody

Western blot analysis of extract from C6 cells using Synapsin antibody Cat.-No AP02760PU Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Synapsin-1 antibody

Western blot analysis of extract from C6 cells using Synapsin antibody Cat.-No AP02760PU Rabbit Aff - Purified Hu, Ms WB
50 µl / €230.00
  Acris Antibodies GmbH

Synapsin-1 pSer549 antibody

Synapsin-1 Rabbit IgG Purified Bov, Can, Hu, Mky, Ms, Rt WB
0.1 ml / €510.00
  Acris Antibodies GmbH

Synapsin-1 antibody

Synapsin-1 Rabbit IgG Purified Bov, Hu, Ms, Rt C, ICC/IF, IP, WB
10 µg / €510.00
  Acris Antibodies GmbH

Synapsin-1 pSer603 antibody

Synapsin-1 Rabbit IgG Purified Bov, Hu, Ms, Rt, Xen, Ze WB
0.1 ml / €510.00
  Acris Antibodies GmbH

Synapsin-1 pSer9 antibody

Synapsin-1 Rabbit IgG Purified Bov, Hu, Ms, Rt, Xen, Ze WB
0.1 ml / €510.00
  Acris Antibodies GmbH

Synapsin-1 antibody

Immunohistochemistry (IHC) analyzes of SYN1 antibody (Cat.-No.: AP06585PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Synapsin-1 pSer549 antibody

Immunostaining of cultured mouse caudate neurons showing synapsin I when phosphorylated at Ser549. Cells and photo courtesy of QBMCellScience. Rabbit IgG Aff - Purified Bov, Can, Hu, Ms, non-Human Primates, Rt C, Dot, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

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