Synaptoporin / SYNPR antibody

Principal name

Synaptoporin / SYNPR antibody

Alternative names for Synaptoporin / SYNPR antibody

MGC26651, Synaptophysin-2

SwissProt ID

P22831 (Rat), Q8BGN8 (Mouse), Q8TBG9 (Human)

Gene ID

132204 (SYNPR), 72003 (Synpr), 66030

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Guinea Pig, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Synaptoporin / SYNPR antibody

Syptophysin (SYP) is a neurol syptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Syptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Syptophysin binds to the SRE protein syptobrevin/VAMP, which prevents the inclusion of syptobrevin in the syptic vesicle fusion complex and creates a pool of syptobrevin for exocytosis when sypse activity increases (3). Syptophysin is also responsible for targeting syptobrevin 2/VAMP2 to syptic vesicles, a critical component of the fusion complex (4).

General readings

Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (2003) Cloning and sequence analysis of the human cDNA encoding the synaptoporin, a highly conserved synaptic vesicle protein. Molecular Biology Reports 30:185-191.Singec I, Knoth R, Ditter M, Hagemeyer CE, Rosenbrock H, Frotscher M, Volk B (2002) Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. J Comp Neurol 452(2):139-153.Grabs D, Bergmann M, Schuster T, Fox PA, Brich M, Gratz M (1994) Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the rat hippocampal network. Eur J Neurosci. 6(11): 1765-71

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptoporin / SYNPR antibody

Synaptoporin / SYNPR Guinea Pig Serum Hu, Ms, Rt C, ICC/IF
0.1 ml / €360.00
  Acris Antibodies GmbH

Synaptoporin / SYNPR (C-term) antibody

Western blot of rat hippocampal lysate showing specific labeling of the ~38k synaptophysin 2  protein. Rabbit IgG Aff - Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptoporin / SYNPR antibody

Predicted band size: 29 kDa . Positive control: Rat brain and mouse brain lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2: Rat brain and mouse brain lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptoporin / SYNPR antibody

WB Suggested Anti-Synpr Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Mouse Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptoporin / SYNPR antibody

Western blot of rat hippocampal lysate showing specific labeling of the ~38k Synpr protein. Using Synpr polyclonal antibody ( Cat # PAB9638 ). Rabbit Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Synaptoporin / SYNPR antibody

Synaptoporin / SYNPR Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

Synaptoporin / SYNPR antibody

Synaptoporin / SYNPR Rabbit Serum Hu, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Synaptoporin / SYNPR antibody

Western Blot:Synaptoporin  Antibody [NB300-738] - Rat hippocampal lysate showing specific labeling of the ~38k Synaptoporin  protein. Rabbit Aff - Purified Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptoporin / SYNPR (transcript variant 2)

Synaptoporin / SYNPR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Synaptoporin / SYNPR (transcript variant 1)

Synaptoporin / SYNPR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SYNPR overexpression lysate

SYNPR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SYNPR overexpression lysate

SYNPR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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