Synaptotagmin-11 antibody

Principal name

Synaptotagmin-11 antibody

Alternative names for Synaptotagmin-11 antibody

Synaptotagmin 11, SYT11, SYT-11, Synaptotagmin XI, SytXI, KIAA0080

SwissProt ID

O08835 (Rat), Q9BT88 (Human), Q9R0N3 (Mouse)

Gene ID

23208 (SYT11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), GP (Guinea Pig), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Synaptotagmin-11 antibody

Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson’s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson’s disease.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-11 antibody

Western blot analysis of extracts from COLO205 cells, using SYT11 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-11 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid and ovarian cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using SYT11 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-11 antibody

Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using SYT11 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-11 antibody

WB Suggested Anti-SYT11 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: MCF7 cell lysate Rabbit IgG Purified GP, Hu, Ms, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-11 antibody

WB Suggested Anti-SYT11 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-11 antibody

Synaptotagmin-11 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Synaptotagmin-11 antibody

Immunofluorescence of monoclonal antibody to SYT11 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 4E1 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Synaptotagmin-11 (N-term) antibody

Synaptotagmin-11 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Synaptotagmin-11 (N-term) antibody

Synaptotagmin-11 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Synaptotagmin-11 antibody

Synaptotagmin-11 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Synaptotagmin-11 antibody

Synaptotagmin-11 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptotagmin-11

Synaptotagmin-11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Synaptotagmin-11

Synaptotagmin-11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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