Synaptotagmin-12 antibody

Principal name

Synaptotagmin-12 antibody

Alternative names for Synaptotagmin-12 antibody

Synaptotagmin 12, SYT12, SYT-12, Synaptotagmin XII, SytXII

SwissProt ID

P97610 (Rat), Q8IV01 (Human), Q920N7 (Mouse)

Gene ID

91683 (SYT12), 171180 (Syt12)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Synaptotagmin-12 antibody

Syptotagmins constitute a family of membranetrafficking proteins that are characterized by an Ntermil transmembrane region (TMR), a variable linker,and two C-termil C2 domains - C2A and C2B. There are 15 members in the mammalian syptotagmin family. There are several C2-domain containing protein families that are related to syptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, syptotagmin-related proteins and B/K) proteins.The syptotagmins are integral membrane proteins of syptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to syptotagmin participates in triggering neurotransmitter release at the sypse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2.Syptotagmin may have a regulatory role in the membrane interactions during trafficking of sypticvesicles at the active zone of the sypse. It binds acidic phospholipids with a specificity that requires thepresence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction betweensyptotagmin and putative receptors for activated protein kise C has also been reported. It can bind to at least three additiol proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2 .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-12 (168-255, Cytopl. Dom.) antibody

Synaptotagmin-12 Mouse IgG1 S277-7 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-12 antibody

WB Suggested Anti-SYT12 Antibody; Titration: 1.0 ug/ml; Positive Control: PANC1 Whole Cell SYT12 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-12 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N277/7 (left) and N86/8 (right). Mouse IgG1 N277/7 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-12 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N277/7 (left) and N86/8 (right). Mouse IgG1 N277/7 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-12 (N-term) antibody

Synaptotagmin-12 Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

Synaptotagmin-12 antibody

Immunofluorescent: Synaptotagmin 12 Antibody [NBP1-03416] - IF on 1 day- old mouse cortical cell culture using Rabbit antibody to c-terminal of Synaptotagmin 12 (SYT12, Synaptotagmin XII): whole serum at 1: 2000 dilution. DAPI counter stained. Rabbit Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Synaptotagmin-12 antibody

Synaptotagmin-12 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Synaptotagmin-12 antibody

Immunohistochemistry-Paraffin: synaptotagmin XII Antibody [NBP1-87001] - Immunohistochemical staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptotagmin-12

Synaptotagmin-12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Synaptotagmin-12

Synaptotagmin-12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Synaptotagmin-12

Synaptotagmin-12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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