Synaptotagmin-12 antibody

Principal name

Synaptotagmin-12 antibody

Alternative names for Synaptotagmin-12 antibody

Synaptotagmin 12, SYT12, SYT-12, Synaptotagmin XII, SytXII

SwissProt ID

P97610 (Rat), Q8IV01 (Human), Q920N7 (Mouse)

Gene ID

91683 (SYT12), 171180 (Syt12), 191595

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Synaptotagmin-12 antibody

Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family.There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins.  The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-12 (168-255, Cytopl. Dom.) antibody

  Mouse Monoclonal Anti-Synaptotagmin-12 Antibody  
Synaptotagmin-12 Mouse IgG1 S277-7 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-12 antibody

  Rabbit Polyclonal Anti-SYT12 Antibody  
WB Suggested Anti-SYT12 Antibody; Titration: 1.0 ug/ml; Positive Control: PANC1 Whole Cell SYT12 is strongly supported by BioGPS gene expression data to be expressed in Human PANC1 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-12 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N277/7 (left) and N86/8 (right). Mouse IgG1 N277/7 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-12 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N277/7 (left) and N86/8 (right). Mouse IgG1 N277/7 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

SYT12 - human gene knockout kit via CRISPR

SYT12 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SYT12 - human gene knockout kit via CRISPR

SYT12 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SYT12 - human gene knockout kit via CRISPR

SYT12 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SYT12 - human gene knockout kit via CRISPR

SYT12 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Syt12 - mouse gene knockout kit via CRISPR

Syt12 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Syt12 - mouse gene knockout kit via CRISPR

Syt12 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Syt12 - mouse gene knockout kit via CRISPR

Syt12 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Syt12 - mouse gene knockout kit via CRISPR

Syt12 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptotagmin-12

  Recombinant protein of human synaptotagmin XII (SYT12)  
Synaptotagmin-12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SYT12 (mGFP-tagged) - Human synaptotagmin XII (SYT12), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT12 (mGFP-tagged) - Human synaptotagmin XII (SYT12), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SYT12 (mGFP-tagged)-Human synaptotagmin XII (SYT12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT12 (mGFP-tagged)-Human synaptotagmin XII (SYT12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SYT12 (Myc-DDK tagged) - Human synaptotagmin XII (SYT12), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT12 (Myc-DDK tagged) - Human synaptotagmin XII (SYT12), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, SYT12 (Myc-DDK-tagged)-Human synaptotagmin XII (SYT12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT12 (Myc-DDK-tagged)-Human synaptotagmin XII (SYT12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Syt12 (GFP-tagged ORF) - Rat synaptotagmin XII (Syt12), 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt12 (GFP-tagged ORF) - Rat synaptotagmin XII (Syt12), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt12 (Myc-DDK-tagged ORF) - Rat synaptotagmin XII (Syt12), 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt12 (Myc-DDK-tagged ORF) - Rat synaptotagmin XII (Syt12), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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