Synaptotagmin-5 antibody

Principal name

Synaptotagmin-5 antibody

Alternative names for Synaptotagmin-5 antibody

Synaptotagmin 5, SYT5, SYT-5, Synaptotagmin V, SytV

SwissProt ID

O00445 (Human), P47861 (Rat), Q9R0N5 (Mouse)

Gene ID

6861 (SYT5), 53420 (Syt5)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Synaptotagmin-5 antibody

Syptotagmins constitute a family of membrane-trafficking proteins that are characterized by an N-termil transmembrane region (TMR), a variable linker, and two C-termil C2 domains - C2A and C2B. There are 15 members in the mammalian syptotagmin family. There are several C2-domain containing protein families that are related to syptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, syptotagmin-related proteins and B/K) proteins.The syptotagmins are integral membrane proteins of syptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to syptotagmin participates in triggering neurotransmitter release at the sypse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2.Syptotagmin may have a regulatory role in the membrane interactions during trafficking of syptic vesicles at the active zone of the sypse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between syptotagmin and putative receptors for activated protein kise C has also been reported. It can bind to at least three additiol proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2 .

General readings

Craxton M.A., Olsen A., et al. (1997), Genomics 42:165-169

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-5 (80-93) antibody

(1ug/ml) staining of Olfactory bulb lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

Predicted band size: 43 kDa . Positive control: Human thigh malignant fibrous histiocytoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 8 hours) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

Predicted band size: 43 kDa . Positive control: Human thigh malignant fibrous histiocytoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 8 hours) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 (253-344, Cytopl. Dom.) antibody

Synaptotagmin-5 Mouse IgG1 S276-15 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

WB Suggested Anti-SYT5 Antibody Titration: 1 ug/ml; Positive Control: Fetal kidney lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N276A/15 (left) and N86/8 (right) Mouse IgG1 N276A/15 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-5 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N276A/15 (left) and N86/8 (right) Mouse IgG1 N276A/15 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-5 antibody

Synaptotagmin-5 Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

Synaptotagmin-5 antibody

Immunofluorescent: Synaptotagmin-5 Antibody [NB100-91298] -  Synaptotagmin-5 Antibody [NB100-91298] - 1 day- old mouse cortical cell culture using Rabbit antibody to rat, mouse Synaptotagmin-5: whole serum at 1:2000 dilution. DAPI counter stained. Rabbit Serum Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Synaptotagmin-5 antibody

Immunohistochemistry-Paraffin: Synaptotagmin 5 Antibody [NBP1-87475] - Immunohistochemical staining of human colon shows strong granular cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptotagmin-5

Synaptotagmin-5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Synaptotagmin-5 (109-386, His-tag)

Synaptotagmin-5 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

Synaptotagmin-5 (109-386, His-tag)

Synaptotagmin-5 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

13 Item(s)

per page
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