Synaptotagmin-5 antibody

Principal name

Synaptotagmin-5 antibody

Alternative names for Synaptotagmin-5 antibody

Synaptotagmin 5, SYT5, SYT-5, Synaptotagmin V, SytV

SwissProt ID

O00445 (Human), P47861 (Rat), Q9R0N5 (Mouse)

Gene ID

6861 (SYT5), 53420 (Syt5), 54309

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Synaptotagmin-5 antibody

Synaptotagmins constitute a family of membrane-trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse.

General readings

Craxton M.A., Olsen A., et al. (1997), Genomics 42:165-169

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-5 (80-93) antibody

  Goat Anti-SYT5/ Synaptotagmin-5 (aa 80-93) Antibody  
(1ug/ml) staining of Olfactory bulb lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

  Anti-SYT5 Rabbit Polyclonal Antibody  
Predicted band size: 43 kDa . Positive control: Human thigh malignant fibrous histiocytoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 8 hours) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

  Anti-SYT5 Rabbit Polyclonal Antibody  
Predicted band size: 43 kDa . Positive control: Human thigh malignant fibrous histiocytoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 8 hours) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 (253-344, Cytopl. Dom.) antibody

  Mouse Monoclonal Anti-Synaptotagmin-9 Antibody  
Synaptotagmin-5 Mouse IgG1 S276-15 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

  Rabbit Polyclonal Anti-SYT5 Antibody  
WB Suggested Anti-SYT5 Antibody Titration: 1 ug/ml; Positive Control: Fetal kidney lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-5 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N276A/15 (left) and N86/8 (right) Mouse IgG1 N276A/15 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-5 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N276A/15 (left) and N86/8 (right) Mouse IgG1 N276A/15 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

SYT5 - human gene knockout kit via CRISPR

SYT5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SYT5 - human gene knockout kit via CRISPR

SYT5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SYT5 - human gene knockout kit via CRISPR

SYT5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SYT5 - human gene knockout kit via CRISPR

SYT5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synaptotagmin-5

  Recombinant protein of human synaptotagmin V (SYT5)  
Synaptotagmin-5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Synaptotagmin-5 (109-386, His-tag)

Synaptotagmin-5 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

Synaptotagmin-5 (109-386, His-tag)

Synaptotagmin-5 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Syt5 (GFP-tagged ORF) - Rat synaptotagmin V (Syt5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt5 (GFP-tagged ORF) - Rat synaptotagmin V (Syt5), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt5 (Myc-DDK-tagged ORF) - Rat synaptotagmin V (Syt5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt5 (Myc-DDK-tagged ORF) - Rat synaptotagmin V (Syt5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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