Synaptotagmin-7 antibody

Principal name

Synaptotagmin-7 antibody

Alternative names for Synaptotagmin-7 antibody

Synaptotagmin 7, SYT7, SYT-7, Synaptotagmin VII, SytVII, IPCA-7, PCANAP7, Prostate cancer-associated protein 7

SwissProt ID

O43581 (Human), Q9R0N7 (Mouse)

Gene ID

9066 (SYT7), 54525 (Syt7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Synaptotagmin-7 antibody

Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family.There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. 
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2.
Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synaptotagmin-7 antibody

  Anti-SYT7 rabbit polyclonal antibody  
Predicted band size: 46kDa. Positive control: Lncap and SKOV3 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: Lncap cell lysate Lane2: SKOV3 cell lysate Lysates: 40 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-7 antibody

  Anti-SYT7 rabbit polyclonal antibody  
Predicted band size: 46kDa. Positive control: SKOV3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-7 (150-239, Cytopl. Dom.) antibody

  Mouse Monoclonal Anti-Synaptotagmin-7 Antibody  
WB of rat brain lysate showing detection of ~65 kDa Synaptotagmin 7 protein using Anti-Synaptotagmin 7.  Lane 1: MW ladder. Lane 2: Anti-Synaptotagmin 7 (1:100). Lane 3: Anti-Synaptotagmin 7 (1:250). Lane 4: Anti-Synaptotagmin 7 (1:500). Lane 5: Anti-Synaptotagmin 7 (1:1000).  Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-Synaptotagmin 7 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 65 kDa. Other band(s) (faint): ~25kDa, ~37kDa, ~100kDa, ~150kDa. Mouse IgG2b S275-14 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-7 antibody

  Mouse Monoclonal anti-Syt 7 Antibody  
Synaptotagmin-7 Mouse IgG1 3C2D4 Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Synaptotagmin-7 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N275/14 (left) and N86/8 (right). Mouse IgG2b N275/14 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Synaptotagmin-7 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin or untagged Kv2.1 plasmids and probed with N275/14 (left) and N86/8 (right). Mouse IgG2b N275/14 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

SYT7 - human gene knockout kit via CRISPR

SYT7 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SYT7 - human gene knockout kit via CRISPR

SYT7 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SYT7 (mGFP-tagged) - Human synaptotagmin VII (SYT7), 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT7 (mGFP-tagged) - Human synaptotagmin VII (SYT7), 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

Lenti ORF particles, SYT7 (Myc-DDK tagged) - Human synaptotagmin VII (SYT7) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SYT7 (Myc-DDK tagged) - Human synaptotagmin VII (SYT7) , 200 uL, >10^7 TU/mL  
200 µl / €890.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (GFP-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,210.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Syt7 (Myc-DDK-tagged) - Mouse synaptotagmin VII (Syt7), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

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