Synphilin 1 / SNCAIP antibody

Principal name

Synphilin 1 / SNCAIP antibody

Alternative names for Synphilin 1 / SNCAIP antibody

Synphilin-1, Sph1, Alpha-synuclein-interacting protein

SwissProt ID

Q99ME3 (Mouse), Q9HC59 (Human), Q9Y6H5 (Human)

Gene ID

9627 (SNCAIP)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection))

Background of Synphilin 1 / SNCAIP antibody

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synphilin 1 / SNCAIP antibody

The anti-Synphilin-1 C-term Pab is used in Western blot to detect Synphilin-1 in mouse brain lysate. Rabbit Ig Purified Hu, Ms E, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Synphilin 1 / SNCAIP (829-847) antibody

Synphilin 1 / SNCAIP Goat Serum Hu P, WB
0.1 ml / €450.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SNCAIP - human gene knockout kit via CRISPR

SNCAIP - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SNCAIP - human gene knockout kit via CRISPR

SNCAIP - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNCAIP - human gene knockout kit via CRISPR

SNCAIP - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNCAIP - human gene knockout kit via CRISPR

SNCAIP - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synphilin 1 / SNCAIP

  Recombinant protein of human synuclein, alpha interacting protein (SNCAIP)  
Synphilin 1 / SNCAIP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

SNCAIP overexpression lysate

SNCAIP overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SNCAIP (mGFP-tagged)-Human synuclein, alpha interacting protein (SNCAIP), 200 uL, >10^7 TU/mL

Lenti ORF particles, SNCAIP (mGFP-tagged)-Human synuclein, alpha interacting protein (SNCAIP), 200 uL, >10^7 TU/mL  
200 µl / €1,920.00
  OriGene Technologies, Inc.

Lenti ORF particles, SNCAIP (Myc-DDK-tagged)-Human synuclein, alpha interacting protein (SNCAIP), 200 uL, >10^7 TU/mL

Lenti ORF particles, SNCAIP (Myc-DDK-tagged)-Human synuclein, alpha interacting protein (SNCAIP), 200 uL, >10^7 TU/mL  
200 µl / €1,730.00
  OriGene Technologies, Inc.

10 Item(s)

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