Synphilin 1 / SNCAIP antibody

Principal name

Synphilin 1 / SNCAIP antibody

Alternative names for Synphilin 1 / SNCAIP antibody

Synphilin-1, Sph1, Alpha-synuclein-interacting protein

SwissProt ID

Q99ME3 (Mouse), Q9HC59 (Human), Q9Y6H5 (Human)

Gene ID

9627 (SNCAIP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), ELISA (detection) (E(detection))

Background of Synphilin 1 / SNCAIP antibody

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shows extensive homology with its human counterpart, especially in regions containing ankyrin-like motifs and the coiled-coil domain. Expression of mouse synphilin-1 in tissues is similar to its human counterpart. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and that Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Role of synphilin-1 in synaptic function and protein degradation and in the molecular mechanisms leading to neurodegeneration in Parkinson disease

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Synphilin 1 / SNCAIP antibody

The anti-Synphilin-1 C-term Pab is used in Western blot to detect Synphilin-1 in mouse brain lysate. Rabbit Ig Purified Hu, Ms E, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Synphilin 1 / SNCAIP (829-847) antibody

Synphilin 1 / SNCAIP Goat Serum Hu P, WB
0.1 ml / €450.00
  Acris Antibodies GmbH

Synphilin 1 / SNCAIP antibody

Synphilin 1 / SNCAIP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP antibody

Western Blot analysis of SNCAIP expression in transfected 293T cell line (H00009627-T02) by SNCAIP MaxPab polyclonal antibody.

Lane 1: SNCAIP transfected lysate(66.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP antibody

Detection limit for recombinant GST tagged SNCAIP is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 2A8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP antibody

Synphilin 1 / SNCAIP Rabbit Hu, Rt C
0.1 ml / €390.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP antibody

The SNCAIP polyclonal antibody ( Cat # PAB4495 ) is used in Western blot to detect SNCAIP in mouse brain lysate . Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP antibody

Immunohistochemical analysis of Synphilin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Synphilin 1 / SNCAIP antibody

Immunohistochemical analysis of Synphilin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Synphilin 1 / SNCAIP antibody

Immunohistochemical analysis of Synphilin 1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Synphilin 1 / SNCAIP antibody

Synphilin 1 / SNCAIP Goat IgG Serum Hu E, P, WB
50 µl / €360.00
  Novus Biologicals Inc.

Synphilin 1 / SNCAIP antibody

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP1-86977] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Synphilin 1 / SNCAIP

Synphilin 1 / SNCAIP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Synphilin 1 / SNCAIP

Synphilin 1 / SNCAIP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP

Synphilin 1 / SNCAIP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP

Synphilin 1 / SNCAIP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Synphilin 1 / SNCAIP

Synphilin 1 / SNCAIP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

SNCAIP 293T Cell Transient Overexpression Lysate(Denatured)

SNCAIP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

SNCAIP overexpression lysate

SNCAIP overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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