SYNPO2 antibody

Principal name

SYNPO2 antibody

Alternative names for SYNPO2 antibody

Synaptopodin-2, Genethonin-2, Myopodin

Gene ID

171024 (SYNPO2)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SYNPO2 antibody

SYNPO2 Antibody: SYNPO2 was initially identified as myopodin, a member of the syptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of sigling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SYNPO2 (N-term) antibody

Western blot analysis of SYNPO2 in human skeletal muscle tissue lysate with SYNPO2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

SYNPO2 control peptide

Western blot analysis of SYNPO2 in human skeletal muscle tissue lysate with SYNPO2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SYNPO2 overexpression lysate

SYNPO2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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