Syntaphilin / SNPH antibody

Principal name

Syntaphilin / SNPH antibody

Alternative names for Syntaphilin / SNPH antibody

KIAA0374

SwissProt ID

B5DF41 (Rat), O15079 (Human), Q6GQX4 (Mouse), Q80U23 (Mouse), Q8IYI3 (Human)

Gene ID

9751 (SNPH), 241727 (Snph), 296267

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Syntaphilin / SNPH antibody

Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait. Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25. Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex, thereby potentially regulating synaptic vesicle exocytosis. Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis. Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria. This correlates with an enhanced short-term facilitation and significant impairments in motor ability, suggesting syntaphilin plays a major role in presynaptic function. Despite its predicted molecular weight, Syntaphilin usually migrates at higher molecular weight in SDS-PAGE. Multiple isoforms are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntaphilin / SNPH antibody

  Rabbit Polyclonal Syntaphilin Antibody  
Western blot analysis of Syntaphilin in human brain tissue lysate with Syntaphilin antibody at (A) 2 and (B) 4 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Syntaphilin / SNPH antibody

  Rabbit Polyclonal Syntaphilin Antibody  
Western blot analysis of Syntaphilin in rat brain tissue lysate with Syntaphilin antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Syntaphilin / SNPH (N-term) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

SNPH - human gene knockout kit via CRISPR

SNPH - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SNPH - human gene knockout kit via CRISPR

SNPH - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNPH - human gene knockout kit via CRISPR

SNPH - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SNPH - human gene knockout kit via CRISPR

SNPH - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snph - mouse gene knockout kit via CRISPR

Snph - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Snph - mouse gene knockout kit via CRISPR

Snph - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snph - mouse gene knockout kit via CRISPR

Snph - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Snph - mouse gene knockout kit via CRISPR

Snph - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Syntaphilin / SNPH

  Recombinant protein of human syntaphilin (SNPH)  
Syntaphilin / SNPH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Syntaphilin / SNPH (1-424, His-tag)

Syntaphilin / SNPH Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

Syntaphilin / SNPH (1-424, His-tag)

Syntaphilin / SNPH Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

SNPH overexpression lysate

SNPH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SNPH (mGFP-tagged) - Human syntaphilin (SNPH), 200 uL, >10^7 TU/mL

Lenti ORF particles, SNPH (mGFP-tagged) - Human syntaphilin (SNPH), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SNPH (Myc-DDK tagged) - Human syntaphilin (SNPH) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SNPH (Myc-DDK tagged) - Human syntaphilin (SNPH) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Snph (GFP-tagged) - Mouse syntaphilin (Snph), 200 uL, >10^7 TU/mL

Lenti ORF particles, Snph (GFP-tagged) - Mouse syntaphilin (Snph), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

Lenti ORF particles, Snph (Myc-DDK-tagged) - Mouse syntaphilin (Snph), 200 uL, >10^7 TU/mL

Lenti ORF particles, Snph (Myc-DDK-tagged) - Mouse syntaphilin (Snph), 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Snph (GFP-tagged ORF) - Rat syntaphilin (Snph), 200 uL, >10^7 TU/mL

Lenti ORF particles, Snph (GFP-tagged ORF) - Rat syntaphilin (Snph), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

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