Syntaxin 2 / STX2 antibody

Principal name

Syntaxin 2 / STX2 antibody

Alternative names for Syntaxin 2 / STX2 antibody

Syntaxin-2, Epimorphin, EPIM, STX2A, STX2B, STX2C

SwissProt ID

P32856 (Human), P50279 (Rat), Q00262 (Mouse), Q20574 (Caeel)

Gene ID

2054 (STX2), 25130 (Stx2)

Available reactivities

Dros (Drosophila), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Bov (Bovine), Can (Canine), Chk (Chicken), Xen (Xenopus), Insect

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), EPair for Elisa (EPair), Frozen Sections (C), Enzyme Immunoassay (E)

Background of Syntaxin 2 / STX2 antibody

Syntaxin 2 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SRE) protein superfamily. The family includes 36 members in humans and is characterized by the SRE motif, an evolutiorily conserved stretch of 60â??70 amino acids that are arranged in heptad repeats. SRE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion. SREs can be roughly divided into vesicular (v-SREs) and target (t-SREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cogte v-/t-SREs between two opposing membranes generates trans-SRE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion. Syntaxin 2, like most SREs, is a type IV membrane protein with a relatively large N-terminus containing the SRE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor. Syntaxin 2 functions as a plasma membrane protein t-SRE, which together with vesicular v-SRE proteins is involved in regulated exocytosis in cells such as platelets, sperm cells and pancreatic acir cells. Intriguingly, Syntaxin 2 has been also identified as epimorphin, an extracellular membrane protein implicated in branching morphogenesis, a developmental process essential for the formation of many organs, including mammary gland, lung, kidney, and salivary gland.

General readings

Abonyo BO., et al. (2004) Biochemistry. 43:3499-3506.Bennett M K., et al. (1993) Cell. 74: 863-873.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntaxin 2 / STX2 antibody

STX2 MaxPab rabbit polyclonal antibody. Western Blot analysis of STX2 expression in human liver. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Syntaxin 2 / STX2 antibody

Western blot analysis of rat brain membranes: 1. Anti-Syntaxin 2 antibody, (1:600). 2. Anti-Syntaxin 2 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Syntaxin 2 / STX2 (1-19) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with STX2 antibody AP22641PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Bov, Can, Chk, Dros, Hst, Hu, Insect, Mky, Ms, Por, Rb, Rt, Sh, Xen IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2 (Center) antibody

Immunohistochemistry in Formalin-fixed, Paraffin embedded human liver tissue stained with Syntaxin 2 / STX2 Antibody (Center) Cat.-No AP54090PU-N  followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2 antibody

EPIM MaxPab polyclonal antibody. Western Blot analysis of EPIM expression in human kidney. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Syntaxin 2 / STX2 antibody

EPIM MaxPab polyclonal antibody. Western Blot analysis of EPIM expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Syntaxin 2 / STX2 antibody

STX2 MaxPab rabbit polyclonal antibody. Western Blot analysis of STX2 expression in human liver. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Syntaxin 2 / STX2 (N-term) antibody

Human Fetal heart; WB Suggested Anti-STX2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Heart; STX2 antibody - N-terminal region (ARP61202_P050) in Human Fetal heart cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Syntaxin 2 / STX2 antibody

Immunohistochemistry-Paraffin: Syntaxin 2 Antibody [NBP1-19338] - Immunohistochemistry analysis of human brain, cerebellum tissue stained with Syntaxin 2, pAb at 10µg/ml. Rabbit Aff - Purified Bov, Can, Chk, Dros, Hu, Mky, Ms, Por, Rb, Rt, Sh, Xen IP, P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

Syntaxin 2 / STX2 antibody

Syntaxin 2 / STX2 Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Syntaxin 2 / STX2 antibody

Syntaxin 2 / STX2 Goat Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Syntaxin 2 / STX2 (transcript variant 2)

Syntaxin 2 / STX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Syntaxin 2 / STX2 (1-264, His-tag)

Syntaxin 2 / STX2 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2 (1-264, His-tag)

Syntaxin 2 / STX2 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2

Syntaxin 2 / STX2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Syntaxin 2 / STX2

Syntaxin 2 / STX2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

STX2 (Human) Matched Antibody Pair

STX2 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

STX2 293T Cell Transient Overexpression Lysate(Denatured)

STX2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

STX2 overexpression lysate

STX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

STX2 overexpression lysate

STX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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