Syntaxin 2 / STX2 antibody

Principal name

Syntaxin 2 / STX2 antibody

Alternative names for Syntaxin 2 / STX2 antibody

Syntaxin-2, Epimorphin, EPIM, STX2A, STX2B, STX2C

SwissProt ID

P32856 (Human), P50279 (Rat), Q00262 (Mouse), Q20574 (Caeel)

Gene ID

2054 (STX2), 25130 (Stx2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Hst (Hamster), Insect, Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Xen (Xenopus)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), EPair for Elisa (EPair), Immunoprecipitation (IP), Paraffin Sections (P)

Background of Syntaxin 2 / STX2 antibody

Syntaxin 2 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SRE) protein superfamily. The family includes 36 members in humans and is characterized by the SRE motif, an evolutiorily conserved stretch of 60â??70 amino acids that are arranged in heptad repeats. SRE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion. SREs can be roughly divided into vesicular (v-SREs) and target (t-SREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cogte v-/t-SREs between two opposing membranes generates trans-SRE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion. Syntaxin 2, like most SREs, is a type IV membrane protein with a relatively large N-terminus containing the SRE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor. Syntaxin 2 functions as a plasma membrane protein t-SRE, which together with vesicular v-SRE proteins is involved in regulated exocytosis in cells such as platelets, sperm cells and pancreatic acir cells. Intriguingly, Syntaxin 2 has been also identified as epimorphin, an extracellular membrane protein implicated in branching morphogenesis, a developmental process essential for the formation of many organs, including mammary gland, lung, kidney, and salivary gland.

General readings

Abonyo BO., et al. (2004) Biochemistry. 43:3499-3506.Bennett M K., et al. (1993) Cell. 74: 863-873.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntaxin 2 / STX2 antibody

  Rabbit Polyclonal Anti-Syntaxin 2  
Western blot analysis of rat brain membranes: 1. Anti-Syntaxin 2 antibody, (1:600). 2. Anti-Syntaxin 2 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Syntaxin 2 / STX2 (1-19) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with STX2 antibody AP22641PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Bov, Chk, Dros, Hst, Hu, Insect, Mky, Ms, Por, Rb, Rt, Sh, Xen IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2 (Center) antibody

Immunohistochemistry in Formalin-fixed, Paraffin embedded human liver tissue stained with Syntaxin 2 / STX2 Antibody (Center) Cat.-No AP54090PU-N  followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Syntaxin 2 / STX2 (transcript variant 2)

  Recombinant protein of human syntaxin 2 (STX2), transcript variant 2  
Syntaxin 2 / STX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Syntaxin 2 / STX2 (1-264, His-tag)

Syntaxin 2 / STX2 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Syntaxin 2 / STX2 (1-264, His-tag)

Syntaxin 2 / STX2 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

STX2 overexpression lysate

STX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

STX2 overexpression lysate

STX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

STX2 overexpression lysate

STX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, STX2 (mGFP-tagged) - Human syntaxin 2 (STX2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, STX2 (mGFP-tagged) - Human syntaxin 2 (STX2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, STX2 (mGFP-tagged) - Human syntaxin 2 (STX2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, STX2 (mGFP-tagged) - Human syntaxin 2 (STX2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, STX2 (Myc-DDK tagged) - Human syntaxin 2 (STX2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, STX2 (Myc-DDK tagged) - Human syntaxin 2 (STX2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, STX2 (Myc-DDK tagged) - Human syntaxin 2 (STX2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, STX2 (Myc-DDK tagged) - Human syntaxin 2 (STX2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

13 Item(s)

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