Syntaxin 4 / STX4 antibody

Principal name

Syntaxin 4 / STX4 antibody

Alternative names for Syntaxin 4 / STX4 antibody

Syntaxin-4, STX4A, NY-REN-31

SwissProt ID

P70452 (Mouse), P91409 (Caeel), Q08850 (Rat), Q12846 (Human), Q3SWZ3 (Bovin), Q7KVY7 (Drome)

Gene ID

6810 (STX4), 81803 (Stx4), 20909 (Stx4a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Syntaxin 4 / STX4 antibody

Syntaxin 4 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SRE) protein superfamily. The family includes 36 members in humans and is characterized by the SRE motif, an evolutiorily conserved stretch of 60–70 amino acids that are arranged in heptad repeats. SRE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion. SREs can be roughly divided into vesicular (v-SREs) and target (t-SREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cogte v-/t-SREs between two opposing membranes generates trans-SRE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion. Syntaxin 4, like most SREs, is a type IV membrane protein with a relatively large N-terminus containing the SRE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor. Syntaxin 4 functions as a plasma membrane protein t-SRE and has been shown to have an important role in pancreatic b-cell insulin secretion and in insulin-stimulated glucose uptake in skeletal muscle and adipose tissue by means of translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane.

General readings

Yang C., et al. (2001) J Clin Invest. 107: 1311-1318Bennett M K., et al. (1993) Cell. 74: 863-873.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntaxin 4 / STX4 antibody

STX4A polyclonal antibody (A01), Lot # 060525JCS1. Western Blot analysis of STX4A expression in NIH/3T3. Mouse Serum Hu, Ms, Rt E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 antibody

STX4 MaxPab rabbit polyclonal antibody. Western Blot analysis of STX4 expression in mouse lung. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 antibody

STX4A monoclonal antibody (M02), clone 6A1. Western Blot analysis of STX4A expression in NIH/3T3(Cat # L018V1 ). Mouse IgG1 6A1 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 antibody

Immunofluorescence of monoclonal antibody to STX4A on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 6D1 Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 antibody

Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA308255 diluted at 1:3000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

Western blot anlysis of rat heart lysate: 1. Anti-Syntaxin 4 antibody , (1:400). 2. Anti-Syntaxin 4 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

WB Suggested Anti-STX4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

WB Suggested Anti-STX4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

STX4A MaxPab polyclonal antibody. Western Blot analysis of STX4A expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 antibody

STX4 MaxPab rabbit polyclonal antibody. Western Blot analysis of STX4 expression in mouse lung. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Syntaxin 4 / STX4 (C-term) antibody

Syntaxin 4 / STX4 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Syntaxin 4 / STX4 antibody

Syntaxin 4 / STX4 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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