Syntaxin 4 / STX4 antibody

Principal name

Syntaxin 4 / STX4 antibody

Alternative names for Syntaxin 4 / STX4 antibody

Syntaxin-4, STX4A, NY-REN-31

SwissProt ID

P70452 (Mouse), P91409 (Caeel), Q08850 (Rat), Q12846 (Human), Q3SWZ3 (Bovin), Q7KVY7 (Drome)

Gene ID

6810 (STX4), 81803 (Stx4), 20909 (Stx4a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Syntaxin 4 / STX4 antibody

Syntaxin 4 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SRE) protein superfamily. The family includes 36 members in humans and is characterized by the SRE motif, an evolutiorily conserved stretch of 60–70 amino acids that are arranged in heptad repeats. SRE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion. SREs can be roughly divided into vesicular (v-SREs) and target (t-SREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cogte v-/t-SREs between two opposing membranes generates trans-SRE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion. Syntaxin 4, like most SREs, is a type IV membrane protein with a relatively large N-terminus containing the SRE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor. Syntaxin 4 functions as a plasma membrane protein t-SRE and has been shown to have an important role in pancreatic b-cell insulin secretion and in insulin-stimulated glucose uptake in skeletal muscle and adipose tissue by means of translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane.

General readings

Yang C., et al. (2001) J Clin Invest. 107: 1311-1318Bennett M K., et al. (1993) Cell. 74: 863-873.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntaxin 4 / STX4 antibody

  Rabbit polyclonal antibody to Syntaxin 4 (syntaxin 4)  
Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA308255 diluted at 1:3000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

  Rabbit Polyclonal Anti-Syntaxin 4  
Western blot anlysis of rat heart lysate: 1. Anti-Syntaxin 4 antibody , (1:400). 2. Anti-Syntaxin 4 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

  Rabbit Polyclonal Anti-STX4 Antibody  
WB Suggested Anti-STX4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Syntaxin 4 / STX4 antibody

  Rabbit Polyclonal Anti-STX4 Antibody  
WB Suggested Anti-STX4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Stx4a - mouse gene knockout kit via CRISPR

Stx4a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

STX4 - human gene knockout kit via CRISPR

STX4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Syntaxin 4 / STX4

  Recombinant protein of human syntaxin 4 (STX4)  
Syntaxin 4 / STX4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Syntaxin 4 / STX4 (1-275, His-tag)

Syntaxin 4 / STX4 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Syntaxin 4 / STX4 (1-275, His-tag)

Syntaxin 4 / STX4 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

STX4 overexpression lysate

STX4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, STX4 (mGFP-tagged) - Human syntaxin 4 (STX4), 200 uL, >10^7 TU/mL

Lenti ORF particles, STX4 (mGFP-tagged) - Human syntaxin 4 (STX4), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, STX4 (Myc-DDK tagged) - Human syntaxin 4 (STX4) , 200 uL, >10^7 TU/mL

Lenti ORF particles, STX4 (Myc-DDK tagged) - Human syntaxin 4 (STX4) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Stx4a (GFP-tagged) - Mouse syntaxin 4A (placental) (Stx4a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Stx4a (GFP-tagged) - Mouse syntaxin 4A (placental) (Stx4a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Stx4a (Myc-DDK-tagged) - Mouse syntaxin 4A (placental) (Stx4a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Stx4a (Myc-DDK-tagged) - Mouse syntaxin 4A (placental) (Stx4a), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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