Syntrophin-1 / SNTA1 antibody

Principal name

Syntrophin-1 / SNTA1 antibody

Alternative names for Syntrophin-1 / SNTA1 antibody

Alpha-1-syntrophin, SNT1, TACIP1, 59 kDa dystrophin-associated protein A1 acidic component 1, Pro-TGF-alpha cytoplasmic domain-interacting protein 1

SwissProt ID

Q0P5E6 (Bovin), Q13424 (Human), Q28626 (Rabit), Q61234 (Mouse)

Gene ID

6640 (SNTA1)

Available reactivities

Amph (Amphibian), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine), Por (Porcine), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Syntrophin-1 / SNTA1 antibody

Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].

General readings

General / background references:Ort T et al. Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion. EMBO J 20:4013-23 (2001). PubMed PMID: 11483505
Ort T et al. The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. Eur J Cell Biol 79:621-30 (2000). PubMed PMID: 11043403
Froehner SC et al. A postsynaptic Mr 58,000 (58K) protein concentrated at acetylcholine receptor-rich sites in Torpedo electroplaques and skeletal muscle. J Cell Biol 104:1633-46 (1987). PubMed PMID: 3294859

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Syntrophin antibody

Western Blot: Syntrophin Antibody(1351) [NB600-1294]-  detection of syntrophin in canine cell lysate using MA1-745. Mouse IgG1 1351 Aff - Purified Amph, Can, Chk, Hu, Ms, Rt ICC/IF, IP, P, WB
50 µg / €340.00
  Novus Biologicals Inc.

Syntrophin-1 / SNTA1 antibody

Anti-SNTA1 mouse monoclonal antibody (TA502040) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). Mouse IgG2b OTI2E12 Purified Can, Hu, Mky, Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

Anti-SNTA1 mouse monoclonal antibody (TA502042) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). Mouse IgG1 OTI1H10 Purified Can, Hu, Mky, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

Anti-SNTA1 mouse monoclonal antibody (TA502045) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). Mouse IgG1 OTI1E9 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 (N-term) antibody

TA302694 (0.01µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide.  Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
20 µg / €200.00
  Acris Antibodies GmbH

Syntrophin-1 / SNTA1 (N-term) antibody

TA302694 (0.01µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide.  Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Syntrophin-1 / SNTA1 antibody

Sample (30 ug of whole cell lysate). A: A549. 10% SDS PAGE. TA308728 diluted at 1:5000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Syntrophin-1 / SNTA1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNTA1 (RC204480, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SNTA1. Mouse IgG2b OTI2E10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

Anti-SNTA1 mouse monoclonal antibody (TA502041) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). Mouse IgG2b OTI2D5 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SNTA1 monoclonal antibody. Mouse IgG2b OTI2B9 Purified Hu, Mky, Rt F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNTA1 (RC204480, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SNTA1. Mouse IgG1 OTI1D4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNTA1 (RC204480, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SNTA1. Mouse IgG2b OTI2A2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SNTA1 (RC204480, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SNTA1. Mouse IgG1 OTI1C7 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

Anti-SNTA1 mouse monoclonal antibody (TA502057) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SNTA1(RC204480). Mouse IgG1 OTI2B4 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Syntrophin-1 / SNTA1 antibody

The cell lysates of HepG2 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SNTA1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1E1 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Syntrophin-1 / SNTA1 antibody

The cell lysates of HepG2 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SNTA1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1E1 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

Syntrophin-1 / SNTA1 antibody

Western Blot analysis of SNTA1 expression in transfected 293T cell line (H00006640-T01) by SNTA1 MaxPab polyclonal antibody.

Lane 1: SNTA1 transfected lysate(55.55 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Syntrophin-1 / SNTA1 antibody

SNTA1 polyclonal antibody ( Cat # PAB6532 ) ( 0.01 µg/ml ) staining of human muscle lysate ( 35 µg protein in RIPA buffer ) with ( A ) and without ( B ) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Syntrophin-1 / SNTA1 antibody

NB 100-1346 staining (0.1µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Syntrophin-1 / SNTA1 antibody

Syntrophin-1 / SNTA1 Rabbit IgG Purified Hu, Rt P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

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