T Cell Receptor / TCR alpha/beta antibody

Principal name

T Cell Receptor / TCR alpha/beta antibody

Alternative names for T Cell Receptor / TCR alpha/beta antibody

TCRA, TCRB, T-Cell Receptor alpha, T-Cell Receptor beta, T-Cell Receptor alpha beta, TCR alpha, TCR beta

Available reactivities

Ms (Mouse), Mky (Monkey), Rt (Rat), Hu (Human), Chk (Chicken)

Available hosts

Hamster, Mouse

Available applications

Flow Cytometry (F), Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of T Cell Receptor / TCR alpha/beta antibody

MAb TCR3 precipitates a CD3-associated heterodimer of Mr 88-kDa (two bands of Mr 48-kDa and 40-kDa upon reduction) on chicken peripheral blood T cells. (1,2) Deglycosylation of the heterodimer yields two polypeptides of Mr 34-kDa and 31-kDa from TCR3 precipitates. In the chicken, two distinct subpopulations of alpha beta T cells appear in the thymus subsequent to the appearance of gamma delta T cells. These subpopulations, originally denoted as TCR2 and TCR3, (1,2) arise sequentially in the thymus during ontogeny and are now known to represent two distinct Vbeta families, Vbeta1 and Vbeta2, respectively. (3) The TCR3 MAb reacts with approximately 9% of thymocytes, 15-25% of blood mononuclear cells and 13% of splenocytes young adult chickens. Two-color immunofluorescence has revealed that the TCR3+ thymocytes include CD4+CD8-, CD4-CD8+, CD4+CD8+ and CD4-CD8- subpopulations. The TCR3+ thymocytes can be separated into two subsets. One subset is characterized by relatively low levels of expression of the TCR3/CD3 complex and most of the cells in this subset are CD4+CD8+. Cells in the other subset express TCR3/CD3 in higher density and are either CD4+CD8- or CD4-CD8+, corresponding to the more mature medullary subset of thymocytes. The TCR3+ cells in the blood and spleen express relatively high levels of the TCR3/CD3 receptor complex and are

General readings

1. Kubo, R.T. Born, W., Kappler, J.W., Marrack, P. and M. Pigeon. 1989.
Characterization of a Monoclonal Antibody Which Detects All Murine ab T Cell Receptors. J. of Immunol. 142:2736-2742.
2. Goodman, T., Lefrancois, L. 1989. Intraepithelial Lymphocytes. J. of Exp. Med. 170: 1569-1581.
3. Gross, J.A., E. Callas and J.P. Allison. 1992. Identification and Distribution of the Costimulatory Receptor CD28 in the Mouse. J. of Immunol. 149: 380-388.
4. Palathumpat, V. et al. 1992. Treatment of BCL1 Leukemia by Transplantation of Low Density Fractions of Allogeneic Bone Marrow and Spleen Cells. J. of Immunol. 148: 3319-3326.
5. Paliwal, V. et al. 1997. Recombinant Soluble ab TCR Receptors Protect T Cells from Immune Suppression. J. of Immunol. 159: 1718-1727.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 APC Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 FITC Hu F
100 Tests / €440.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 Biotin Hu F
0.1 mg / €260.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 FITC Hu F
100 Tests / €260.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 Aff - Purified Hu F
0.1 mg / €210.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 IP26 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

Figure 1 Hamster IgG H57-597 Biotin Ms F

Regular Price: 0.1 mg / €220.00

Special Price: 0.1 mg / €168.00

  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

Figure 1 Hamster IgG H57-597 Biotin Ms F
0.3 mg / €370.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

Percentage of Cells Stained Above Control: A / 76.9% B / 90.3% Hamster IgG H57-597 FITC Ms F
0.1 mg / €230.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Hamster IgG H57-597 FITC Ms F
0.3 mg / €370.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Hamster IgG H57-597 PE Ms F
50 µg / €230.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Hamster IgG H57-597 PE Ms F
0.3 mg / €540.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

SM321F staining of rat splenocytes. Mouse IgG1 R73 FITC Mky, Rt F
0.1 mg / €430.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

Staining of rat spleen cells with Mouse anti Rat TCR alpha/beta Low Endotoxin (Cat.-No SM321LE). Mouse IgG1 R73 Low Endotoxin Mky, Rt C, F, FN, IP
0.5 mg / €570.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 R73 Purified Mky, Rt C, F, IP
0.25 mg / €430.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 R73 PE Mky, Rt F
100 Tests / €530.00
  Acris Antibodies GmbH

T Cell Receptor (TCR) alpha/beta antibody

T Cell Receptor (TCR) alpha/beta Mouse IgG1 R73 Biotin Mky, Rt F
0.1 mg / €360.00
  Novus Biologicals Inc.

T Cell Receptor (TCR) alpha/beta antibody

Flow Cytometry: TCR ALPHA/BETA Antibody (R73) [NB100-64275] - Staining of rat splenocytes. Mouse IgG1 R73 FITC Mky, Rt F, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

T Cell Receptor (TCR) alpha/beta antibody

Flow cytometry / FACS analysis: TCR alpha / beta Antibody (H57-597) [FITC] [NBP1-28061] - The T195 T-cell line was first incubated with purified hamster anti-mouse TCR?d and then stained with mouse anti-hamster IgG-FITC. Large cells were gated and analyzed by flow cytometry. Hamster IgG H57-597 FITC Ms C, F, IP, P
0.25 mg / €600.00
  Novus Biologicals Inc.

T Cell Receptor (TCR) alpha/beta antibody

Flow cytometry / FACS analysis: TCR alpha / beta Antibody (H57-597) [Biotin] [NBP1-28062] - The T195 T-cell line was first incubated with purified hamster anti-mouse TCR alpha/beta and then stained with mouse anti-hamster IgG-FITC. Large cells were gated and analyzed by flow cytometry. Hamster IgG H57-597 Biotin Ms C, F, IP, P
0.25 mg / €600.00
  Novus Biologicals Inc.

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