TAB1 / MAP3K7IP1 antibody

Principal name

TAB1 / MAP3K7IP1 antibody

Alternative names for TAB1 / MAP3K7IP1 antibody

TAK1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1

SwissProt ID

Q15750 (Human), Q8CF89 (Mouse)

Gene ID

10454 (TAB1), 66513 (Tab1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Enzyme Immunoassay (E), Dot blot (Dot)

Background of TAB1 / MAP3K7IP1 antibody

The specific function of the protein remains unknown.The protein encoded by this gene was identified as a regulator of the MAP kise kise kise MAP3K7/TAK1, which is known to mediate various intracellular sigling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kise. It has been shown that the C-termil portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a domint-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kise 14 (MAPK14/p38alpha), and thus represents an altertive activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Altertively spliced transcript variants encoding distinct isoforms have been reported.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TAB1 / MAP3K7IP1 antibody

  Rabbit Polyclonal TAB1 Antibody  
Western blot analysis of TAB1 in 3T3 cell lysate with TAB1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TAB1 / MAP3K7IP1 antibody

  Rabbit anti-MAP3K7IP1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using MAP3K7IP1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TAB1 / MAP3K7IP1 antibody

  Rabbit Polyclonal Anti-TAB1 Antibody  
WB Suggested Anti-TAB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TAB1 / MAP3K7IP1 antibody

  Mouse Monoclonal TAB1(N-terminus) Antibody  
Western blot detection of TAB1(N-terminus) in K562 and Hela lysates using TAB1(N-terminus) mouse mAb (1:1000 diluted).Predicted band size: 55KDa.Observed band size: 55KDa. Mouse 3D10-G10-B6 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TAB1 / MAP3K7IP1 antibody

  Rabbit Polyclonal Anti-TAB1 Antibody  
TAB1 /  MAP3K7IP1 Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TAB1 / MAP3K7IP1 antibody

TAB1 /  MAP3K7IP1 Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €390.00
  Acris Antibodies GmbH

TAB1 / MAP3K7IP1 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Kidney. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TAB1 / MAP3K7IP1 antibody

Figure 1. Western blot analysis of MAP3K7IP1 (arrow) using Rabbit polyclonal MAP3K7IP1 pSer438 (Cat.#AP09519PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MAP3K7IP1 gene (Lane 2) (Origene Technologies). Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TAB1 / MAP3K7IP1 antibody

Western blot analysis of MAP3K7IP1 (arrow) using rabbit polyclonal MAP3K7IP1-pS423 (AP17544PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAP3K7IP1 gene (Lane 2) (Origene Technologies). Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Tab1 - mouse gene knockout kit via CRISPR

Tab1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tab1 - mouse gene knockout kit via CRISPR

Tab1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tab1 - mouse gene knockout kit via CRISPR

Tab1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tab1 - mouse gene knockout kit via CRISPR

Tab1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TAB1 / MAP3K7IP1 (transcript variant alpha)

  Recombinant protein of human mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha  
TAB1 /  MAP3K7IP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TAB1 overexpression lysate

TAB1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tab1 (GFP-tagged) - Mouse TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tab1 (GFP-tagged) - Mouse TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tab1 (Myc-DDK-tagged) - Mouse TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tab1 (Myc-DDK-tagged) - Mouse TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1), 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

17 Item(s)

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