TAB2 / MAP3K7IP2 antibody

Principal name

TAB2 / MAP3K7IP2 antibody

Alternative names for TAB2 / MAP3K7IP2 antibody

TAK1-binding protein 2, Tab-2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2

SwissProt ID

Q5U303 (Rat), Q99K90 (Mouse), Q9NYJ8 (Human)

Gene ID

23118 (TAB2)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of TAB2 / MAP3K7IP2 antibody

TAB2 Antibody: TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kise complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the sigl transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.

General readings

Kanayama, A., et al., ,(2004) Mol. Cell 15 (4), 535-548

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TAB2 / MAP3K7IP2 (C-term) antibody

Immunohistochemistry of TAB2 in human brain tissue with TAB2 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

TAB2 / MAP3K7IP2 antibody

WB Suggested Anti-MAP3K7IP2 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysateTAB2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TAB2 / MAP3K7IP2 antibody

Western blot analysis using TAB2 antibody Cat.-No AM06537SU-N against HEK293 (1) and TAB2(AA: 1-300)-hIgGFc transfected HEK293 (2) cell lysate. Mouse IgG1 3B5 Ascites Hu E, F, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

TAB2 / MAP3K7IP2 (79-90) antibody

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Platypus, Prim, Rb, Rt, Tr P
50 µg / €470.00
  Acris Antibodies GmbH

TAB2 / MAP3K7IP2 (161-173) antibody

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt, Tr P
50 µg / €470.00
  Acris Antibodies GmbH

TAB2 / MAP3K7IP2 (C-term) Control Peptide

TAB2 / MAP3K7IP2
50 µg / €160.00
  Acris Antibodies GmbH

TAB2 / MAP3K7IP2 antibody

Western Blot analysis of MAP3K7IP2 expression in transfected 293T cell line (H00023118-T01) by MAP3K7IP2 MaxPab polyclonal antibody.

Lane 1: MAP3K7IP2 transfected lysate(76.23 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TAB2 / MAP3K7IP2 antibody

TAB2 / MAP3K7IP2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TAB2 / MAP3K7IP2 antibody

Immunoprecipitation of MAP3K7IP2 transfected lysate using anti-MAP3K7IP2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with MAP3K7IP2 MaxPab mouse polyclonal antibody (B01) (H00023118-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

TAB2 / MAP3K7IP2 antibody

Human Spermatophore; MAP3K7IP2 antibody - N-terminal region (ARP32402_P050) in Human Spermatophore cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

TAB2 / MAP3K7IP2 antibody

Western Blot: TAB2 Antibody [NBP1-46199]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Affinity purified rabbit anti-TAB2 antibody A302-758A used for IP at 3 mcg/mg lysate.  TAB2 was also immunoprecipitated by rabbit anti-TAB2 antibody NBP1-46200, which recognizes a downstream epitope. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

TAB2 / MAP3K7IP2 antibody

Western Blot: TAB2 Antibody [NBP1-46200]-Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. Affinity purified rabbit anti-TAB2 antibody NBP1-46199 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  TAB2 was also immunoprecipitated by rabbit anti-TAB2 antibody A302-758A, which recognizes an upstream epitope. Rabbit Aff - Purified Hu, Ms IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TAB2 / MAP3K7IP2 antibody

Western Blot: TAB2 Antibody (3B5) [NBP1-51668] - Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2-hIgGFc transfected HEK293 (2) cell lysate. Mouse IgG1 3B5 Purified Hu E, F, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MAP3K7IP2 293T Cell Transient Overexpression Lysate(Denatured)

MAP3K7IP2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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