TAB3 / MAP3K7IP3 antibody

Principal name

TAB3 / MAP3K7IP3 antibody

Alternative names for TAB3 / MAP3K7IP3 antibody

TAK1-binding protein 3, NF-kappa-B-activating protein 1, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3

SwissProt ID

Q571K4 (Mouse), Q8N5C8 (Human)

Gene ID

257397 (TAB3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P)

Background of TAB3 / MAP3K7IP3 antibody

TAB3 Antibody: TAB3 functions in the NF-kappaB sigl transduction pathway. It and the similar and functiolly redundant protein TAB2, form a terry complex with the protein kise TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent TAK1 kise activity triggers a sigling cascade leading to activation of the NF-kappaB transcription factor. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.

General readings

Cheung PC, Nebreda AR, and Cohen P. TAB3, a new binding partner of the protein kinase TAK1. Biochem. J. 2004; 378:27-34.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TAB3 / MAP3K7IP3 (N-term) antibody

Immunohistochemistry of TAB3 in human kidney tissue with TAB3 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

TAB3 / MAP3K7IP3 (N-term) Control Peptide

TAB3 / MAP3K7IP3
50 µg / €160.00
  Acris Antibodies GmbH

TAB3 / MAP3K7IP3 antibody

Western blot analysis of MAP3K7IP3 in human kidney lysate in the 1 ) absence and 2 ) presence of immunizing peptide. Using MAP3K7IP3 polyclonal antibody ( Cat # PAB0304 ) at 0.5 µg/ml. Rabbit Hu, Ms WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TAB3 / MAP3K7IP3 antibody

TAB3 / MAP3K7IP3 Goat Hu, Ms E
0.1 mg / €390.00
  Abnova Taiwan Corp.

TAB3 / MAP3K7IP3 antibody

TAB3 / MAP3K7IP3 Goat Hu, Ms E
0.1 mg / €390.00
  Abnova Taiwan Corp.

TAB3 / MAP3K7IP3 antibody

Western Blot and Immunoprecipitation: TAB3 antibody[NBP1-26592]-Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. TAB3 was also immunoprecipitated by rabbit anti-TAB3 antibody NBP1-26593. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TAB3 / MAP3K7IP3 antibody

Western Blot: TAB3 Antibody [NBP1-26593]- Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells. Affinity purified  rabbit used for IP at 10 mcg/mg  lysate. TAB3 was also immunoprecipitated by rabbit anti-TAB3  antibody NBP1-26592, which recognizes an upstream epitope Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

TAB3 / MAP3K7IP3 antibody

Immunohistochemistry-Paraffin: TAB3 Antibody [NBP1-81262] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in goblet cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TAB3 / MAP3K7IP3

TAB3 / MAP3K7IP3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

TAB3 / MAP3K7IP3

TAB3 / MAP3K7IP3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TAB3 / MAP3K7IP3

TAB3 / MAP3K7IP3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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