Tapasin (TAPBP) antibody

Principal name

Tapasin (TAPBP) antibody

Alternative names for Tapasin (TAPBP) antibody

TPSN, TPN, TAPA, NGS17, NGS-17, TAP-binding protein, TAP-associated protein

SwissProt ID

O15533 (Human), O73895 (Chick), Q5TJE4 (Canfa), Q9R233 (Mouse)

Gene ID

6892 (TAPBP), 21356 (Tapbp)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Tapasin (TAPBP) antibody

TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

General readings

"Tapasin is required for efficient peptide binding to transporter associated with antigen processing." Li S., Paulsson K.M., Chen S., Sjoegren H.-O., Wang P. J. Biol. Chem. 275:1581-1586(2000) [PubMed: 10636848]

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tapasin (TAPBP) antibody

Hum. Fetal Muscle; Host: Rabbit. Target Name: NOP56 . Sample Tissue: Human Fetal Muscle . Antibody Dilution: 1.0ug/ml.; TAPBP antibody - middle region (ARP45438_P050) in Hum. Fetal Muscle cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Tapasin (TAPBP) antibody

Western blot analysis of extracts of various cell lines, using TAPBP antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tapasin (TAPBP) (N-term) antibody

Human 293T; WB Suggested Anti-TAPBP Antibody Titration: 0.2-1 ug/ml. Positive Control: 293T cell lysate; TAPBP antibody - N-terminal region (AP46045PU-N) in Human 293T cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  Acris Antibodies GmbH

Tapasin (TAPBP) (N-term) antibody

Human 293T; WB Suggested Anti-TAPBP Antibody Titration: 0.2-1 ug/ml. Positive Control: 293T cell lysate; TAPBP antibody - N-terminal region (ARP45436_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Tapasin (TAPBP) antibody

Human Skin; TAPBP antibody - C-terminal region (ARP45437_P050) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tapasin (TAPBP) (transcript variant 1)

Tapasin (TAPBP) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tapasin (TAPBP)

Tapasin (TAPBP) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Tapasin (TAPBP)

Tapasin (TAPBP) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TAPBP (mGFP-tagged) - Human TAP binding protein (tapasin) (TAPBP), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TAPBP (mGFP-tagged) - Human TAP binding protein (tapasin) (TAPBP), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TAPBP (Myc-DDK tagged) - Human TAP binding protein (tapasin) (TAPBP), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TAPBP (Myc-DDK tagged) - Human TAP binding protein (tapasin) (TAPBP), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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