TARDBP antibody

Principal name

TARDBP antibody

Alternative names for TARDBP antibody

TDP43, TDP-43, TAR DNA-binding protein 43

SwissProt ID

Q13148 (Human), Q5ZLN5 (Chick), Q921F2 (Mouse)

Gene ID

23435 (TARDBP), 230908 (Tardbp)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Bov (Bovine), African clawed frog, Xen (Xenopus), Ze (Zebrafish), Prim (Primate), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of TARDBP antibody

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

General readings

Buratti,E., (2005) J. Biol. Chem. 280 (45), 37572-37584

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CRISPR

Catalog No. Species Donor Vector  

TARDBP - human gene knockout kit via CRISPR

TARDBP - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TARDBP - human gene knockout kit via CRISPR

TARDBP - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TARDBP

  Recombinant protein of human TAR DNA binding protein (TARDBP)  
TARDBP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TARDBP (1-260, His-tag)

TARDBP Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  OriGene Technologies GmbH

TARDBP (1-260, His-tag)

TARDBP Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  OriGene Technologies GmbH

TARDBP (1-414, His-tag)

TARDBP Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

TARDBP (1-414, His-tag)

TARDBP Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TARDBP (mGFP-tagged) - Human TAR DNA binding protein (TARDBP), 200 uL, >10^7 TU/mL

Lenti ORF particles, TARDBP (mGFP-tagged) - Human TAR DNA binding protein (TARDBP), 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.

Lenti ORF particles, TARDBP (Myc-DDK tagged) - Human TAR DNA binding protein (TARDBP) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TARDBP (Myc-DDK tagged) - Human TAR DNA binding protein (TARDBP) , 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (GFP-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tardbp (Myc-DDK-tagged) - Mouse TAR DNA binding protein (Tardbp), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

Items 21 to 37 of 37 total

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