TBX1 antibody

Principal name

TBX1 antibody

Alternative names for TBX1 antibody

T-box protein 1, T-box transcription factor TBX1, Testis-specific T-box protein

SwissProt ID

O43435 (Human), P70323 (Mouse), Q8AXX2 (Danre)

Gene ID

6899 (TBX1), 21380 (Tbx1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of TBX1 antibody

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

General readings

Yamagishi,H., et al., (2003) Genes Dev. 17 (2), 269-281

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TBX1 (C-term) antibody

  Rabbit polyclonal TBX1 Antibody (C-term)  
TBX1 Antibody (C-term) (Cat.# TA325103) western blot analysis in HLVEC cell line lysates (35ug/lane).This demonstrates the TBX1 antibody detected the TBX1 protein (arrow). Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

TBX1 antibody

  Rabbit polyclonal anti-TBX1 antibody  
Western blot analysis of extracts from COLO205 cells, using TBX1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TBX1 antibody

  Rabbit Polyclonal Anti-TBX1 Antibody  
WB Suggested Anti-TBX1 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TBX1 antibody

  Rabbit Polyclonal Anti-TBX1 Antibody  
WB Suggested Anti-TBX1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Lung Rabbit IgG Purified Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TBX1 antibody

  Rabbit Polyclonal Anti-TBX1 Antibody  
Western blot analysis on COLO205 cell lysate using TBX1 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TBX1 antibody

  TBX1 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-TBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507326) Mouse IgG1 OTI1C2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TBX1 antibody

Western blot (WB) analysis of TBX1 antibody (Cat.-No.: AP06637PU-N) in extracts from COLO 205 cells. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TBX1 antibody

Immunofluorescence analysis of A549 cells, using TBX1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

TBX1 antibody

Immunofluorescence analysis of A549 cells, using TBX1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

TBX1 - human gene knockout kit via CRISPR

TBX1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TBX1 - human gene knockout kit via CRISPR

TBX1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TBX1 - human gene knockout kit via CRISPR

TBX1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TBX1 - human gene knockout kit via CRISPR

TBX1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tbx1 - mouse gene knockout kit via CRISPR

Tbx1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tbx1 - mouse gene knockout kit via CRISPR

Tbx1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tbx1 - mouse gene knockout kit via CRISPR

Tbx1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tbx1 - mouse gene knockout kit via CRISPR

Tbx1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TBX1 (transcript variant A)

  Recombinant protein of human T-box 1 (TBX1), transcript variant A  
TBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TBX1 (transcript variant C)

  Purified recombinant protein of Homo sapiens T-box 1 (TBX1), transcript variant C  
TBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TBX1 overexpression lysate

TBX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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