TCCR / IL27RA antibody

Principal name

TCCR / IL27RA antibody

Alternative names for TCCR / IL27RA antibody

T-cell cytokine receptor type 1, IL-27R-alpha, WSX-1, WSX1, CRL1, UNQ296/PRO336, Interleukin-27 receptor subunit alpha

SwissProt ID

O70394 (Mouse), Q6UWB1 (Human)

Gene ID

9466 (IL27RA), 50931 (Il27ra)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of TCCR / IL27RA antibody

The IL-27 Receptor complex includes WSX-1 and gp130. IL-27R (WSX-1) is 65-70 kDa protein and is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes including CD4+ and CD8+ T cells, monocytes, DCs and NK cells (1-3). IL-27R activation includes STAT1, STAT3, STAT4 and STAT5, leading to differing pathway dependent effector activities. Like the IL12/IL-12R complex, the IL-27/IL-27R complex also has Th1 enhancing activity especially enhancement of IFNg production by ive T cells and NK cells (1). IL-27R mediates downregulation of Th2 activity by findings that IL-27R deficiencies mitigate inflammatory pathology in helminthic infections in mice (1, 4, 5). The possibility of utilizing IL-27R as a target for autoimmune inflammatory diseases, especially of mucosal surfaces as in human IBD, is under investigation, measured by Th2 type cytokines and bolstered through Th2

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TCCR / IL27RA antibody

  Mouse Monoclonal IL-27 R alpha/WSX-1/TCCR Antibody (34N4G11)  
Immunohistochemistry-Paraffin: IL27RA Antibody (34N4G11) [TA336909] - Adenocarcinoma of the stomach probed with IL-27R antibody at 5 ug/ml. Mouse IgG2b 34N4G11 Purified Hu F, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

TCCR / IL27RA (N-term) antibody

  Rabbit Polyclonal TCCR Antibody  
Western blot analysis of TCCR expression in human spleen tissue lysates with TCCR antibody at 1 ug /ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TCCR / IL27RA (C-term) antibody

  Rabbit Polyclonal TCCR Antibody  
Western blot analysis of TCCR expression in human spleen tissue lysate with TCCR antibody at 1 ug /ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TCCR / IL27RA antibody

  Rabbit Polyclonal Anti-IL27RA Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse thymus tissue, Mouse heart tissue, Primary antibody: (IL27RA Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TCCR / IL27RA antibody

Spleen: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TCCR / IL27RA antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, Cortex. Rabbit Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

IL27RA - human gene knockout kit via CRISPR

IL27RA - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IL27RA - human gene knockout kit via CRISPR

IL27RA - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

IL27RA - human gene knockout kit via CRISPR

IL27RA - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

IL27RA - human gene knockout kit via CRISPR

IL27RA - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Il27ra - mouse gene knockout kit via CRISPR

Il27ra - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Il27ra - mouse gene knockout kit via CRISPR

Il27ra - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Il27ra - mouse gene knockout kit via CRISPR

Il27ra - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Il27ra - mouse gene knockout kit via CRISPR

Il27ra - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TCCR / IL27RA

  Recombinant protein of human interleukin 27 receptor, alpha (IL27RA)  
TCCR / IL27RA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IL27RA overexpression lysate

IL27RA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IL27RA (mGFP-tagged) - Human interleukin 27 receptor, alpha (IL27RA), 200 uL, >10^7 TU/mL

Lenti ORF particles, IL27RA (mGFP-tagged) - Human interleukin 27 receptor, alpha (IL27RA), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, IL27RA (Myc-DDK tagged) - Human interleukin 27 receptor, alpha (IL27RA) , 200 uL, >10^7 TU/mL

Lenti ORF particles, IL27RA (Myc-DDK tagged) - Human interleukin 27 receptor, alpha (IL27RA) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Il27ra (Myc-DDK-tagged) - Mouse interleukin 27 receptor, alpha (Il27ra), 200 uL, >10^7 TU/mL

Lenti ORF particles, Il27ra (Myc-DDK-tagged) - Mouse interleukin 27 receptor, alpha (Il27ra), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

19 Item(s)

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