TCEB2 antibody

Principal name

TCEB2 antibody

Alternative names for TCEB2 antibody

Elongin 18 kDa subunit, Elongin-B, Elongin B, EloB, Transcription elongation factor B polypeptide 2, RNA polymerase II transcription factor SIII subunit B

SwissProt ID

P62869 (Mouse), P62870 (Rat), Q15370 (Human)

Gene ID

6923 (TCEB2), 67673 (Tceb2), 81807

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of TCEB2 antibody

TCEB2 is the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

General readings

Piessevaux J., et al. (2008) J Biol Chem. 283(31):21334-46.Duan DR., et al. (1995) Science. 269(5229):1402-6

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TCEB2 antibody

  Rabbit Polyclonal anti-TCEB2 antibody  
WB Suggested Anti-TCEB2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TCEB2 antibody

  Rabbit anti-TCEB2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TCEB2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TCEB2 antibody

Hela cell nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-elongin B Antibody (Clone 10C4). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence system. Mouse IgG1 10C4 Biotin Hu WB
0.1 mg / €400.00
  Acris Antibodies GmbH

TCEB2 antibody

Hela cell nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Elongin B Antibody  (Clone 10C4) Cat.-No AM33055PU-N. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence system. Mouse IgG1 10C4 Purified Hu IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TCEB2 antibody

Hela cell nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-Elongin B Antibody  (Clone 10C4) Cat.-No AM33055PU-N. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence system. Mouse IgG1 10C4 Purified Hu IP, WB
25 µg / €210.00
  Acris Antibodies GmbH

TCEB2 (N-term) antibody

TCEB2 Antibody (N-term) (Cat. #AP54200PU-N) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the TCEB2 antibody detected the TCEB2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TCEB2 - human gene knockout kit via CRISPR

TCEB2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TCEB2 - human gene knockout kit via CRISPR

TCEB2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TCEB2 - human gene knockout kit via CRISPR

TCEB2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TCEB2 - human gene knockout kit via CRISPR

TCEB2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tceb2 - mouse gene knockout kit via CRISPR

Tceb2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tceb2 - mouse gene knockout kit via CRISPR

Tceb2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tceb2 - mouse gene knockout kit via CRISPR

Tceb2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tceb2 - mouse gene knockout kit via CRISPR

Tceb2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TCEB2 (transcript variant 1)

  Recombinant protein of human transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) (TCEB2), transcript variant 1  
TCEB2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TCEB2 (transcript variant 2)

  Recombinant protein of human transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) (TCEB2), transcript variant 2  
TCEB2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

TCEB2 (1-118) (recombinant)

TCEB2 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

TCEB2 (1-118) (recombinant)

TCEB2 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €240.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

TCEB2 overexpression lysate

TCEB2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TCEB2 overexpression lysate

TCEB2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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