TCIRG1 / ATP6N1C antibody

Principal name

TCIRG1 / ATP6N1C antibody

Alternative names for TCIRG1 / ATP6N1C antibody

V-ATPase 116 kDa isoform a3, ATP6V0A3, V-type proton ATPase 116 kDa subunit a isoform 3, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, Osteoclastic proton pump 116 kDa subunit, T-cell immune regulator 1, T-cell immune response cDNA7 protein

SwissProt ID

Q13488 (Human)

Gene ID

10312 (TCIRG1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of TCIRG1 / ATP6N1C antibody

Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq]. Transcript Variant: This variant (1) encodes isoform a, also known as the OC116 protein because it is one of three V-ATPase 116 kD subunits. It is also referred to as the a3 isoform and is induced on osteoclast differentiation. This variant contains a unique 5' end and lacks an internal segment compared to variant 2, which results in an isoform (a) with a different N-terminus than that of isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Toyomura T, Oka T, Yamaguchi C, et al. Three subunit a isoforms of mouse vacuolar H+-ATPase. Preferential expression of the a3 isoform during osteoclast differentiation. J. Biol. Chem. 2000; 275:8760-5
Kornak U, Schulz A, Friedrich W, et al. Mutations in the a3 subunit of the vacuolar H+-ATPase cause malignant osteopetrosis. Hum. Mol. Genet. 2000; 9:2059-63.
Sun-Wada GH, Toyomura T, Kawamura N, et al. The a3 isoform of V-ATPase regulates insulin secretion from pancreatic b-cells. J. Cell Sci. 2006; 119:4531-40.
Sun-Wada GH, Tabata H, Kawamura N, et al. Direct recruitment of H+-ATPase from lysosomes for phagocytic acidification. J. Cell Sci. 2009; 122:2504-13.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TCIRG1 / ATP6N1C (N-term) antibody

Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TCIRG1 / ATP6N1C antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCIRG1 (RC202125, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCIRG1. Rabbit IgG Purified Hu, Ms E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TCIRG1 / ATP6N1C (N-term) Control Peptide

TCIRG1 / ATP6N1C
50 µg / €160.00
  Acris Antibodies GmbH

TCIRG1 / ATP6N1C antibody

TCIRG1 / ATP6N1C Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

Western Blot analysis of TCIRG1 expression in transfected 293T cell line (H00010312-T02) by TCIRG1 MaxPab polyclonal antibody.

Lane 1: TCIRG1 transfected lysate(68.80 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

TCIRG1 / ATP6N1C Mouse IgG2a 6H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

TCIRG1 / ATP6N1C Mouse IgG2a 6H3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

TCIRG1 / ATP6N1C Mouse IgG1 7H20 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

TCIRG1 / ATP6N1C Mouse IgG1 7H20 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C antibody

ELISA: TCIRG1 Antibody [43480002] Rabbit Hu E, WB
50 µg / €480.00
  Novus Biologicals Inc.

TCIRG1 / ATP6N1C antibody

Immunohistochemistry-Paraffin: TCIRG1 Antibody [NBP1-89333] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TCIRG1 / ATP6N1C

TCIRG1 / ATP6N1C Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TCIRG1 overexpression lysate

TCIRG1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TCIRG1 overexpression lysate

TCIRG1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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