TCR V beta 8.1 8.2 antibody

Principal name

TCR V beta 8.1 8.2 antibody

Alternative names for TCR V beta 8.1 8.2 antibody

T Cell Receptor V beta 8.1, 8.2

Available reactivities

Ms (Mouse)

Available hosts

Rat

Available applications

Flow Cytometry (F)

Background of TCR V beta 8.1 8.2 antibody

T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level.

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