TDRD1 antibody

Principal name

TDRD1 antibody

Alternative names for TDRD1 antibody

Tudor domain-containing protein 1, CT41.1, Cancer/testis antigen 41.1

SwissProt ID

Q99MV1 (Mouse), Q9BXT4 (Human)

Gene ID

56165 (TDRD1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of TDRD1 antibody

Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Participates in branch migration and Holliday junction resolution and thus is important for processing HR intermediates late in the DNA repair process. Also has an early function in DNA repair in facilitating phosphorylation of the checkpoint kinase CHK2 and thereby transduction of the damage signal, leading to cell cycle arrest and HR activation. Protects RAD51 from ubiquitin-mediated degradation that is enhanced following DNA damage. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and XRCC3. Contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Involved in maintaining centrosome number in mitosis.

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TDRD1 (C-term) antibody

TDRD1 Antibody (C-term) (AP54211PU-N) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the TDRD1 antibody detected the TDRD1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TDRD1 antibody

Western Blot analysis of TDRD1 expression in transfected 293T cell line (H00056165-T02) by TDRD1 MaxPab polyclonal antibody.

Lane 1: TDRD1 transfected lysate(130.79 KDa).
Lane 2: Non-transfected lysate. Mouse Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TDRD1 antibody

Immunohistochemistry-Paraffin: TDRD1 Antibody [NBP1-84348] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells of tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

TDRD1 antibody

Immunohistochemistry-Paraffin: TDRD1 Antibody [NBP1-84349] - Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in cells in seminiferus ducts and leydig cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

TDRD1 293T Cell Transient Overexpression Lysate(Denatured)

TDRD1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TDRD1 overexpression lysate

TDRD1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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