Tectonic-1 antibody

Principal name

Tectonic-1 antibody

Alternative names for Tectonic-1 antibody

TCTN1,TECT1

SwissProt ID

Q2MV58 (Human), Q8BZ64 (Mouse)

Gene ID

79600 (TCTN1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of Tectonic-1 antibody

TCTN1 Antibody: TCTN1 is the founding member of the Tectonic protein family, a group of evolutiorily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh sigling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh sigling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tectonic-1 antibody

Western blot analysis of TCNT1 using Uninduced Jurkat cell lysate (Lane1), Induced Jurkat cell lysate (Lane 2), mouse 3T3 cell lysate (Lane 3) and rat kidney tissue lysate (Lane 4). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tectonic-1 antibody

Western blot analysis of TCNT1 using Jurkat cell lysate (Lane1) and rat kidney tissue lysate (Lane 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tectonic-1 (N-term) antibody

Western blot analysis of TCTN1 in mouse kidney tissue lysate with TCTN1 antibody at (A) 1 and (B) 2ug/mL. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tectonic-1 antibody

Tectonic-1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Tectonic-1 antibody

Immunohistochemistry-Paraffin: TCTN1 Antibody [NBP1-77182] - Human kidney tissue with TCTN1 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Tectonic-1 antibody

Immunohistochemistry-Paraffin: TCTN1 Antibody [NBP1-83623] - Immunohistochemical staining of human placenta shows strong cytoplasmic and nuclear positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Tectonic-1 antibody

Immunohistochemistry-Paraffin: TCTN1 Antibody [NBP1-83624] Immunohistochemical staining of human kidney shows distinct cytoplasmic and membranous positivity in tubular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tectonic-1 (transcript variant 2)

Tectonic-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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