Tectonic-3 antibody

Principal name

Tectonic-3 antibody

Alternative names for Tectonic-3 antibody

TCTN3, TECT3, C10orf61

SwissProt ID

Q6NUS6 (Human), Q8R2Q6 (Mouse)

Gene ID

26123 (TCTN3), 67590 (Tctn3)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Tectonic-3 antibody

Tect3 (tectonic-3), also known as TCTN3, is a 607 amino acid single-pass type I membrane protein that belongs to the tectonic family and exists as four altertively spliced isoforms. Tect3 interacts with MKS1 and may be involved in apoptosis regulation. The gene that encodes Tect3 contains approximately 31,560 bases and maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs and encoding nearly 1,200 genes, chromosome 10 makes up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman¡¯s syndrome, Cowden syndrome, Cockayne syndrome, multiple endocrine neoplasia type 2 and porphyria. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.

General readings

Reiter,J.F. (2006) Genes Dev. 20 (1), 22-27

4 Item(s)

per page

CRISPR

Catalog No. Species Donor Vector  

TCTN3 - human gene knockout kit via CRISPR

TCTN3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TCTN3 - human gene knockout kit via CRISPR

TCTN3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TCTN3 - human gene knockout kit via CRISPR

TCTN3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TCTN3 - human gene knockout kit via CRISPR

TCTN3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

4 Item(s)

per page
  • LinkedIn