Telethonin / TCAP antibody

Principal name

Telethonin / TCAP antibody

Alternative names for Telethonin / TCAP antibody

Titin cap protein

SwissProt ID

O15273 (Human), O70548 (Mouse), Q6T8D8 (Bovin)

Gene ID

8557 (TCAP), 21393 (Tcap)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Telethonin / TCAP antibody

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human TCAP with an internal ID of S23001

General readings

Bos,J.M., (2008) Am. Heart J. 155 (6), 1128-1134

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI5E12 (formerly 5E12)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2a OTI5E12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI6C1 (formerly 6C1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2a OTI6C1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI8E6 (formerly 8E6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2b OTI8E6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI1A7 (formerly 1A7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG1 OTI1A7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI7H5 (formerly 7H5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2b OTI7H5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI6D3 (formerly 6D3)  
Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808352)(1:150) Mouse IgG1 OTI6D3 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI11H10 (formerly 11H10)  
Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA808419)(1:150) Mouse IgG1 OTI11H10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

  TCAP mouse monoclonal antibody, clone OTI3E7 (formerly 3E7)  
Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808437)(1:150) Mouse IgG1 OTI3E7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

TCAP - human gene knockout kit via CRISPR

TCAP - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tcap - mouse gene knockout kit via CRISPR

Tcap - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tcap - mouse gene knockout kit via CRISPR

Tcap - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tcap - mouse gene knockout kit via CRISPR

Tcap - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tcap - mouse gene knockout kit via CRISPR

Tcap - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Telethonin / TCAP (full length, N-term HIS tag)

  Recombinant protein of human titin-cap (telethonin) (TCAP) , full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
Telethonin / TCAP Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TCAP (mGFP-tagged) - Human titin-cap (telethonin) (TCAP), 200 uL, >10^7 TU/mL

Lenti ORF particles, TCAP (mGFP-tagged) - Human titin-cap (telethonin) (TCAP), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, TCAP (Myc-DDK tagged) - Human titin-cap (telethonin) (TCAP) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TCAP (Myc-DDK tagged) - Human titin-cap (telethonin) (TCAP) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tcap (GFP-tagged) - Mouse titin-cap (Tcap), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tcap (GFP-tagged) - Mouse titin-cap (Tcap), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tcap (Myc-DDK-tagged) - Mouse titin-cap (Tcap), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tcap (Myc-DDK-tagged) - Mouse titin-cap (Tcap), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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