Telethonin / TCAP antibody

Principal name

Telethonin / TCAP antibody

Alternative names for Telethonin / TCAP antibody

Titin cap protein

SwissProt ID

O15273 (Human), O70548 (Mouse), Q6T8D8 (Bovin)

Gene ID

8557 (TCAP)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Telethonin / TCAP antibody

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human TCAP with an internal ID of S23001

General readings

Bos,J.M., (2008) Am. Heart J. 155 (6), 1128-1134

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Telethonin / TCAP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2a OTI5E12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2a OTI6C1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2b OTI8E6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG1 OTI1A7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCAP (RC203158, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCAP.(1:2000) Mouse IgG2b OTI7H5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808352)(1:150) Mouse IgG1 OTI6D3 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA808419)(1:150) Mouse IgG1 OTI11H10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TCAP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808437)(1:150) Mouse IgG1 OTI3E7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Telethonin / TCAP antibody

Detection limit for recombinant GST tagged TCAP is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 2B1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Telethonin / TCAP antibody

Detection limit for recombinant GST tagged TCAP is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 1H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Telethonin / TCAP antibody

Telethonin / TCAP Mouse IgM 1A3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Telethonin / TCAP antibody

Human Liver; WB Suggested Anti-TCAP Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Liver; TCAP antibody - N-terminal region (ARP48227_P050) in Human Liver cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Telethonin / TCAP antibody

Human HepG2; WB Suggested Anti-TCAP Antibody Titration: 5.0ug/ml. Positive Control: HepG2 cell lysate; TCAP antibody - middle region (ARP48228_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Telethonin / TCAP antibody

Western Blot: TCAP Antibody [NBP1-56626] - This Anti-TCAP antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 5ug/ml. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Telethonin / TCAP antibody

Western Blot: TCAP Antibody [NBP1-56664] - This Anti-TCAP antibody was used in Western Blot of Fetal Liver tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Telethonin / TCAP antibody

Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Immunohistochemical staining of human heart muscle shows distinct cytoplasmic positivity. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Telethonin / TCAP (full length, N-term HIS tag)

Telethonin / TCAP Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Telethonin / TCAP

Telethonin / TCAP Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Telethonin / TCAP

Telethonin / TCAP Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Telethonin / TCAP

Telethonin / TCAP Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

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