Tenascin / TNC / HXB antibody

Principal name

Tenascin / TNC / HXB antibody

Alternative names for Tenascin / TNC / HXB antibody

Tenascin-C, TN-C, Hexabrachion, Cytotactin, Neuronectin, GMEM, Myotendinous antigen, Glioma-associated-extracellular matrix antigen, GP 150-225

SwissProt ID

P10039 (Chick), P24821 (Human), Q29116 (Pig), Q80YX1 (Mouse)

Gene ID

3371 (TNC), 21923 (Tnc)

Available reactivities

Hu (Human), GP (Guinea Pig), Rb (Rabbit), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Tenascin / TNC / HXB antibody

Tenascins were first characterized in the early 1980’s. Since then hundreds of publications on tenascin in normal tissues, pathologically reactive tissues and carcinomas have been published. However, only recently more elective studies have been done. In these studies retrospective material from pathology files has been studied as well as larger fresh material collected during several years from patients. These studies have now attempted to reveal more specific points in carcinogenesis and pathological tissue reactions. 
It has been demonstrated that tenascin immunoreactivity in breast carcinoma cells could be indicative of metastasis and survival. Recent studies using retrospective material showed that the expression of tenascin in invasion border of early breast cancer significantly correlates with higher risk of distant metastasis. These studies have been continued now and the preliminary results clearly suggest that expression of tenascin in invasion border of early breast cancer is significantly associated with proliferative activity and higher risk of local recurrence. This result implicates a wide application for tenascin antibodies in the breast pathology.

The point is that tenascin expression may suggest situations in which even small breast carcinomas may need more intensive complementary therapy (chemotherapy etc.). Recent studies have also shown that tenascin is significantly increased in airway basement membrane of asthmatics and rapidly decreases by inhaled steroid. This result suggests that tenascin expression may be used to monitor the disease status and outcome of treatment in different types of asthma.

  1. Quick-Filters:
  2. Cited (1)

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tenascin / TNC / HXB antibody

Immunohistochemistry staining of tonsil (paraffin-embedded sections) with anti-Human Tenascin antibody (T2H5) Cat.-No BM722S. Mouse IgG1 T2H5 Purified Hu E, IP, P, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

Tenascin / TNC / HXB antibody

  Mouse Monoclonal Tenascin C Antibody (4C8MS)  
Immunohistochemistry: Tenascin C Antibody (4C8MS) - Immunohistochemical analysis of Tenascin C on mouse bone and tendon using anti-Tenascin C. Mouse IgG1 4C8MS Purified Hu, Ms, Rt C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Anti-TNC Rabbit Polyclonal Antibody  
Predicted cell location: Secreted,Extracellular matrix. Positive control: Human esophagus cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using TNC antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Rabbit Polyclonal Tenascin C Antibody  
ELISA: Tenascin C Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Rabbit Polyclonal Tenascin C Antibody  
ELISA: Tenascin C Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Rabbit Polyclonal Tenascin C Antibody  
ELISA: Tenascin C Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Rabbit Polyclonal Tenascin C Antibody  
ELISA: Tenascin C Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

  Rabbit Polyclonal Tenascin C Antibody  
ELISA: Tenascin C Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB antibody

Immunohistochemistry on paraffin Human mammary cancer sections Mouse IgG1 T20 Purified Hu C, ICC/IF, IP, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Tenascin / TNC / HXB antibody

Tenascin / TNC / HXB Mouse IgG2a DB7 Ig Fraction Hu C, ICC/IF, IP, P, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

Tenascin / TNC / HXB antibody

Tenascin / TNC / HXB Mouse IgG1 EB2 Ig Fraction GP, Hu, Rb C, E, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TNC - human gene knockout kit via CRISPR

TNC - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TNC - human gene knockout kit via CRISPR

TNC - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnc - mouse gene knockout kit via CRISPR

Tnc - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tnc - mouse gene knockout kit via CRISPR

Tnc - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnc - mouse gene knockout kit via CRISPR

Tnc - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnc - mouse gene knockout kit via CRISPR

Tnc - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tenascin / TNC / HXB

  Recombinant protein of human tenascin C (TNC)  
Tenascin / TNC / HXB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tenascin / TNC / HXB

Tenascin / TNC / HXB Human Purified > 97 % pure by SDS PAGE. Precipitated, concentrated and dialysed.
0.1 mg / €600.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TNC (Myc-DDK tagged) - Human tenascin C (TNC), 200 uL, >10^7 TU/mL

Lenti ORF particles, TNC (Myc-DDK tagged) - Human tenascin C (TNC), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
  • LinkedIn