TER ATPase / VCP antibody

Principal name

TER ATPase / VCP antibody

Alternative names for TER ATPase / VCP antibody

15S Mg(2+)-ATPase p97 subunit, Valosin-containing protein, Transitional endoplasmic reticulum ATPase

SwissProt ID

P03974 (Pig), P23787 (Xenla), P46462 (Rat), P55072 (Human), Q01853 (Mouse), Q3ZBT1 (Bovin), Q7KN62 (Drome), Q7ZU99 (Danre)

Gene ID

7415 (VCP), 5327197 (IPR007158), 327197 (vcp)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Rb (Rabbit), Xen (Xenopus), Por (Porcine), Ze (Zebrafish), Bov (Bovine)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), PLA/Proximity ligation assay (PLA), Enzyme Immunoassay (E)

Background of TER ATPase / VCP antibody

P97/VCP (valosin containing protein) belongs to the AAA ATPase family, predicted molecular weight 97 kD. VCP is associated with a variety of cellular activities, including cell cycle control, membrane fusion after mitosis, regulates spindle disassembly at the end of mitosis, nuclear trafficking and the ubiquitin-proteasome degradation pathway. In many instances, specific adaptor proteins with which VCP forms multiprotein complexes direct its role in a given process. This protein is required for the fusion of ER and Golgi membranes. 
Structure: Belongs to the AAA ATPase family, homohexamer, forms a ring-shaped particle of 12.5 nm diameter and displays 6-fold radial symmetry.
Interaction: VCIP135, SELS/VIMP, SYVN1, DERL1, DERL2, DERL3, SVIP.
Bioactivity/Activities: VCP is associated with a variety of cellular activities, including cell cycle control, membrane fusion after mitosis, regulates spindle disassembly at the end of mitosis, nuclear trafficking and the ubiquitin-proteasome degradation pathway.

General readings

1. Peknicova J, Kyselova V, Buckiova D, Boubelik M.: Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage. Am J Reprod Immunol. 2002 May;47(5):311-8.
2. Pavlasek J, Peknicova J, Ulcova-Gallova Z, Novakova P, Reischig J, Micanova Z, Rokyta Z.: Significance of determination of intra-acrosomal proteins and sperm antibodies in human reproduction. Ceska Gynekol. 2004 Jul;69(4):306-11.
3. Tepla O. et al. In: In vitro Fertilization & Human Reproductive Genetics, ed. Monduzzi, Bologna, 107, (1999).
4. Chladek D, Peknicova J, Capkova J, Geussova G, Tepla O, Madar J.: Use of human sperm protein monoclonal antibodies in the diagnosis of sperm pathology and selection of a suitable assisted reproduction method for fertilization. Ceska Gynekol. 2000 Jan;65(1):28-32. Czech.
5. Peknicova J, Chladek D, Hozak P.: Monoclonal antibodies against sperm intra-acrosomal antigens as markers for male infertility diagnostics and estimation of spermatogenesis.
Am J Reprod Immunol. 2005 Jan;53(1):42-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TER ATPase / VCP antibody

Immunohistochemical of  paraffin-embedded human colon cancer using 10736-1-AP(VCP antibody) at dilution of 1:50 (under 40x lens) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, IP, P, WB
0.15 ml / €285.00
  Proteintech Group, Inc.

TER ATPase / VCP antibody

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 60316-1-Ig( VCP Antibody) at dilution of 1:50 (under 40x lens) Mouse IgG1 2A4B10 Purified Hu, Ms E, ICC/IF, P, WB
0.15 ml / €285.00
  Proteintech Group, Inc.

TER ATPase / VCP antibody

Immunohistochemistry was performed on cancer biopsies of deparaffinized Human colon carcinoma tissues. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1/1000 with SM5062 or with primary antibody (Negative Control) overnight at 4°C. in humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting. Mouse IgG2a 5 Ascites Hu, Ms, Rt C, F, ICC/IF, IP, P, WB
0.1 ml / €470.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Immunohistochemical analysis of paraffin-embedded breast ca, using VCP(GTX101089) antibody at 1:500 dilution. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.


Sample size available for 25µl / 119€
read more…

TER ATPase / VCP antibody

Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using VCP(p97)(GTX113030) antibody at 1:500 dilution. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.


Sample size available for 25µl / 119€
read more…

TER ATPase / VCP antibody

VCP antibody [N3C2], Internal detects VCP protein at nucleus on gastric carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded gastric carcinoma. VCP antibody [N3C2], Internal (GTX113099) dilution: 1:500. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.


Sample size available for 25µl / 119€
read more…

TER ATPase / VCP antibody

Figure 1. Immunofluorescence analysis of 220 kDa intra-acrosomal protein in Acetone-permeabilized Human sperms using monoclonal antibody AM03029 Clone Hs-14 (normal spermiogram). Mouse IgM Hs-14 FITC Hu, Ms F
50 Tests / €360.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Immunofluorescence analysis of 220 kDa intra-acrosomal protein in acetone-permeabilized human sperms using monoclonal antibody Hs-14 (normal spermiogram). Mouse IgM Hs-14 Purified Hu, Ms F, ICC/IF, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Formalin-Fixed Paraffin-Embedded Human Prostate tissue stained with p97/VCP Antibody Cat.-No AM08335PU (Clone 4G9)  at 5 µg/ml after heat-induced antigen retrieval. Mouse IgG1 4G9 Aff - Purified Hu ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Formalin-Fixed Paraffin-Embedded Human Prostate tissue stained with p97/VCP Antibody Cat.-No AM08335PU (Clone 4G9)  at 5 µg/ml after heat-induced antigen retrieval. Mouse IgG1 4G9 Aff - Purified Hu ICC/IF, IP, P, WB
25 µg / €220.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 4A8 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

TER ATPase / VCP (C-term) antibody

Western blot analysis of VCP Antibody (C-term) (AP17823PU-N) in Jurkat, 293, MDA-MB231 cell line lysates (35ug/lane). VCP (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €360.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

Immunohistochemistry (IHC) analyzes of VCP antibody (Cat.-No.: AP21142PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

TER ATPase / VCP Mouse IgG1 58.13.3 Supernatant Hu, Rb, Rt, Xen WB
0.5 ml / €300.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

TER ATPase / VCP Mouse IgG1 58.13.3 Purified Hu, Rb, Rt, Xen WB
50 µg / €310.00
  Acris Antibodies GmbH

TER ATPase / VCP Control Peptide

TER ATPase / VCP Purified
50 µg / €220.00
  Acris Antibodies GmbH

TER ATPase / VCP antibody

TER ATPase / VCP Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 ml / €400.00
  GeneTex Inc.

TER ATPase / VCP antibody

Immunohistochemical staining of paraffin-embedded human brain tissue using anti-VCP RabMAb (cat. #GTX62520). Rabbit IgG EPR3308 Supernatant Hu, Ms P, WB
0.1 ml / €420.00
  GeneTex Inc.

TER ATPase / VCP antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-VCP RabMAb (cat. #GTX62809). Rabbit IgG EPR3307(2) Supernatant Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 ml / €450.00
  GeneTex Inc.

TER ATPase / VCP antibody

Immunohistochemical analysis of paraffin-embedded zebrafish tissue, using vcp (GTX124821) antibody at 1:300 dilution. Rabbit IgG Purified Ze P, WB
50 µl / €270.00
  GeneTex Inc.

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